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FNAC联合FNA-Tg在老年甲状腺乳头状癌颈部淋巴结转移诊断中的应用研究
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Abstract:
目的：探讨颈部淋巴结细针穿刺病理(fine needle aspiration cytodiagnosis, FNAC)联合检测穿刺针洗脱液甲状腺球蛋白(Thyroglobulin measurement in fine-needle aspiration biopsy, FNA-Tg)检测对老年甲状腺乳头状癌(PTC)颈淋巴结转移患者的应用价值。方法：回顾性分析2021年3月至2021年11月齐齐哈尔市第一医院甲状腺外科疑似为甲状腺乳头状癌颈淋巴结转移老年病人40例的临床资料，所以患者均接受FNAC病理学检查及FNA-Tg检测，以术后病理结果作为金标准，比较单独FNAC与两者联合检测的诊断诊断价值。结果：两者联合检测的敏感性、阴性预测值、准确率为均显著高单独FNAC (P < 0.05)，有统计学意义。结论：应用FNAC联合FNA-Tg检测技术是一种简便易行的诊断方法，在诊断甲状腺乳头状癌淋巴结转移具有较高的诊断效能，值得临床推广应用。
Objective: To investigate the value of fine needle aspiration biopsy (FNAC) combined with thy-roglobulin (FNA-Tg) detection in needle elution in cervical lymph node metastasis of elderly pa-tients with papillary thyroid carcinoma (PTC). Methods: The clinical data of 40 elderly patients sus-pected of cervical lymph node metastasis of papillary thyroid cancer in the thyroid surgery de-partment of the First Hospital of Qiqihar City from March 2021 to November 2021 were analyzed retrospectively. All patients received FNAC pathological examination and FNA-Tg detection. With the postoperative pathological results as the gold standard, the diagnostic value of FNAC alone and their combined detection was compared. Results: The sensitivity, negative predictive value and ac-curacy rate of the combined detection were significantly higher than those of FNAC alone (P < 0.05). Conclusion: FNAC combined with FNA-Tg detection technology is a simple and easy diagnostic method, which has high diagnostic efficacy in the diagnosis of lymph node metastasis of thyroid pa-pillary carcinoma, and is worthy of clinical application.
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