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肝切除术后肝衰竭的研究进展
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Abstract:
肝切除术后肝衰竭(PHLF)是肝切除术后一种极为严重的并发症，严重影响着肝切除术患者术后的生存时间。总结其定义、诊断标准、影响PHLF的因素、术前肝脏储备功能评估方法及预防措施，得出了术前积极进行肝脏功能评估和合理设计手术方式，术中精细操作减少出血和保留更多的功能性肝脏体积，术后早期评估肝功能和积极识别肝衰竭的发生对于减少PHLF的发生有重要意义，改善患者的预后。
Post-hepatectomy liver failure (PHLF) is an extremely serious complication after hepatectomy, which seriously affects the survival time of hepatectomy patients after surgery. Summarizing its definition, pathogenesis, factors leading to PHLF, preventive measures and preoperative liver func-tion assessment methods, we concluded that active preoperative liver function assessment and ra-tional design of surgical approach, precise intraoperative operation to reduce bleeding and pre-serve more functional liver volume, early postoperative assessment of liver function and active identification of liver failure are important to reduce the occurrence of PHLF and improve the prog-nosis of patients.
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