|
Nursing Science 2022
基于大数据的艾条改善肿瘤患者失眠穴位选取的研究与实践
|
Abstract:
目的:分析基于大数据下选取穴位进行艾灸对肿瘤失眠患者的临床疗效。方法:选择2020年07月~2021年04月就诊于福建中医药大学附属第二人民医院普外科患者,符合相关诊断标准和纳入标准的结直肠癌手术后化疗失眠患者80例,按照住院先后顺序随机分成治疗组(40例)和对照组(40例)。对照组采用常规住院治疗,治疗组在此基础上进行艾灸治疗。比较2组入院第1 d,化疗第1 d、第3 d及化疗周期结束日患者失眠量表评分、癌症疲乏状态(CFS)及生活质量评分(FACT-G)。统计并比较2组治疗期间所发生的不良反应情况。结果:治疗组化疗第3 d及化疗周期结束日失眠量表评分低于对照组(P < 0.05);治疗组化疗第3 d及化疗周期结束日CFS评分低于对照组(P < 0.05);治疗组化疗第3 d及化疗周期结束日FACT-G评分高于对照组(P < 0.05);治疗期间2组均未发生严重不良反应。结论:基于大数据下选取穴位进行艾灸对肿瘤失眠患者疗效确切,可改善患者失眠状况,明显缓解患者癌症疲乏状态,提高患者生活质量,且不增加不良反应发生风险。
Objective: Analyze the clinical efficacy of moxibustion at selected acupoints based on big data on patients with tumor insomnia. Methods: From July 2020 to April 2021, 80 patients with insomnia after chemotherapy for colorec-tal cancer who met the relevant diagnostic criteria and inclusion criteria were selected for treat-ment at the Second People’s Hospital of Fujian University of Traditional Chinese Medicine. They were randomly divided into groups according to the order of hospitalization: Treatment group (40 cases) and control group (40 cases). The control group was treated with conventional hospitaliza-tion, and the treatment group was treated with moxibustion on this basis. The first day of admission, the first day, the third day of chemotherapy and the end of the chemotherapy cycle on the insomnia scale score, cancer fatigue status (CFS) and quality of life assessment (FACT-G) were compared be-tween the two groups. The adverse reactions that occurred during the treatment of the two groups were counted and compared. Results: The scores of the Insomnia Scale on the 3rd day of chemo-therapy and the end of the chemotherapy cycle in the treatment group were lower than those in the control group (P < 0.05). The CFS score of the treatment group on the 3rd day of chemotherapy and the end of the chemotherapy cycle was lower than that of the control group (P < 0.05). The FACT-G score of the treatment group on the 3rd day of chemotherapy and the end of the chemotherapy cy-cle was higher than that of the control group (P < 0.05). No serious adverse reactions occurred in both groups during treatment. Conclusions: Moxibustion on selected acupoints based on big data has a definite effect on patients with tumor insomnia, which can improve the patient’s insomnia, significantly alleviate the patient’s cancer fatigue, improve the patient’s quality of life, and does not increase the risk of adverse reactions.
[1] | Piawah, S. and Venook, A.P. (2019) Targeted Therapy for Colorectal Cancer Metastases: A Review of Current Methods of Molecularly Targeted Therapy and the Use of Tumor Biomarkers in the Treatment of Metastatic Colorectal Cancer. Cancer, 125, 4139-4147. https://doi.org/10.1002/cncr.32163 |
[2] | Schieber, K., Niecke, A., Geiser, F., Erim, Y., Bergelt, C., Büttner-Teleaga, A., et al. (2019) The Course of Cancer-Related Insomnia: Don’t Expect It to Disappear after Cancer Treatment. Sleep Medicine, 58, 107-113.
https://doi.org/10.1016/j.sleep.2019.02.018 |
[3] | Yue, H., Zhou, S., Wu, H., Yin, X., Li, S., Liang, T., et al. (2020) Efficacy and Safety of Electro-Acupuncture (EA) on Insomnia in Patients with Lung Cancer: Study Protocol of a Ran-domized Controlled Trial. Trials, 21, Article No. 788.
https://doi.org/10.1186/s13063-020-04721-4 |
[4] | Garland, S.N., Xie, S.X., Du Hamel, K., Bao, T., Li, Q., Barg, F.K., et al. (2019) Acupuncture versus Cognitive Behavioral Therapy for Insomnia in Cancer Survivors: A Randomized Clinical Trial. Journal of the National Cancer Institute, 111, 1323-1331. https://doi.org/10.1093/jnci/djz050 |
[5] | Yuan, T., Xiong, J., Wang, X., Yang, J., Jiang, Y., Zhou, X., et al. (2019) The Effectiveness and Safety of Moxibustion for Treating Knee Osteoarthritis: A PRISMA Compliant Systematic Re-view and Meta-Analysis of Randomized Controlled Trials. Pain Research and Management, 2019, Article ID: 2653792. https://doi.org/10.1155/2019/2653792 |
[6] | 中华人民共和国卫生和计划生育委员会医政医管局, 中华医学会肿瘤学分会. 中国结直肠癌诊疗规范(2017年版) [J]. 中国医学前沿杂志(电子版), 2018, 10(3): 1-21. |
[7] | 中华医学会神经病学分会, 中华医学会神经病学分会睡眠障碍学组. 中国成人失眠诊断与治疗指南(2017版) [J]. 中华神经科杂志, 2018, 51(5): 324-335. |
[8] | Tu, M., Wang, F., Shen, S., Wang, H. and Feng, J. (2021) Influences of Psy-chological Intervention on Negative Emotion, Cancer-Related Fatigue and Level of Hope in Lung Cancer Chemotherapy Patients Based on the PERMA Framework. Iranian Journal of Public Health, 50, 728-736. https://doi.org/10.18502/ijph.v50i4.5997 |
[9] | Song, L., Tan, X., Bredle, J., Bennett, A.V. and Northouse, L. (2020) Psychometric Properties of the FACT-G Quality of Life Scale for Family Caregivers of Cancer Patients. Quality of Life Research, 29, 2241-2252.
https://doi.org/10.1007/s11136-020-02477-7 |
[10] | Shahrokhi, M., Ghaeli, P., Arya, P., Shakiba, A., Noormandi, A., Soleimani, M., et al. (2021) Comparing the Effects of Melatonin and Zolpidem on Sleep Quality, Depression, and Anxi-ety in Patients with Colorectal Cancer Undergoing Chemotherapy. Basic and Clinical Neuroscience, 12, 105-114. https://doi.org/10.32598/bcn.12.1.1650.2 |
[11] | Savard, J. and Ivers, H. (2019) Screening for Clinical Insomnia in Cancer Patients with the Edmonton Symptom Assessment System-Revised: A Specific Sleep Item Is Needed. Support Care Cancer, 27, 3777-3783.
https://doi.org/10.1007/s00520-019-4662-2 |
[12] | Zhou, X., Wu, Q., Zhang, G., Wang, Y., Li, S., Wang, B., et al. (2020) Heat-Sensitive Moxibustion Self-Administration in Patients in the Community with Primary Hypertension: A Protocol for a Multi-Center, Pragmatic, Non-Randomized Trial. Medicine, 99, e22230. https://doi.org/10.1097/MD.0000000000022230 |
[13] | 赖永金, 马淑娟, 魏威. 热敏灸联合佐匹克隆对卒中后睡眠障碍患者睡眠质量的影响[J]. 医学理论与实践, 2020, 33(11): 1771-1773. |
[14] | Hu, H., Chen, L., Jin, X., Li, R. and Fang, J. (2020) Effect of Herb-Partitioned Moxibustion on Pain and Quality of Life in Women with Endometriosis: A Protocol for a Randomized Clinical Trial. Journal of Traditional Chinese Medicine, 40, 324-332. |
[15] | Shin, S., Jang, B.H., Park, S.H., Lee, J.W., Chae, M.S., Kim, N., et al. (2019) Effectiveness, Safety, and Economic Evaluation of Adju-vant Moxibustion Therapy for Aromatase Inhibitor-Induced Arthralgia of Postmenopausal Breast Cancer Stage I to III Patients: Study Protocol for a Prospective, Randomized, Assessor-Blind, Usual-Care Controlled, Parallel-Group, Pilot Clinical Trial. Medicine, 98, e17260. https://doi.org/10.1097/MD.0000000000017260 |