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Evaluation of the Fetal Neuroprotection Protocol with Magnesium Sulphate in a University Hospital in Burkina Faso

DOI: 10.4236/ojog.2022.1210087, PP. 1042-1055

Keywords: Premature Delivery, Fetal Neuroprotection, Sulfates Magnesium, UHC of Yal-gado Ouedraogo, UHC of Bogodogo, Burkina Faso

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Abstract:

Introduction: Prematurity continues to stand as a major public health issue worldwide and more particularly for low incomes countries like Burkina Faso. Indeed, it is the main cause of high death rate and infant morbidity, neurologic deficiencies being one of them. Objective: From March 1st to September 30th, 2020, evaluate the fetal neuroprotection protocol using sulfate magnesium during births before thirty-three (33) weeks of amenorrhea at the University Health Centers (UHC) of Yalgado Ouedraogo and Bogodogo in Ouagadougou, Burkina Faso. Patients and Methods: It was a prospective cohort survey, exposed or unexposed. The exposed ones are from the UHC of Yalgado Ouedraogo, while the unexposed ones are from the UHC of Bogodogo. Analysis of the results showed 87 newborns from the exposed and 180 from the unexposed. The mortality rate, as well as neonatal neurologic complications, was higher with unexposed than with exposed. Although antenatal exposure to magnesium sulfate was not statistically associated with mortality and morbidity in newborns at a threshold of 0.05%, it has shown an overall good neurological prognosis in newborns exposed. Conclusion: A

References

[1]  Hassoune, S., Tsoumbou, B.G., Boussouf, N. and Nani, S. (2018) Extent of Prematurity in the Greater Maghreb Countries: A Systematic Review. Tunis Medical Journal, 96, 628-635.
[2]  World Health Organization (2012) Born Too Soon: The Global Action Report on Preterm Birth. World Health Organization, Genève, 126.
[3]  World Health Organization (2015) Recommendations on Interventions to Improve Preterm Birth Outcomes. World Health Organization, Geneva.
[4]  Crowther, C.A., Hiller, J.E., Doyle, L.W., Haslam, R.R. and Australasian Collaborative Trial of Magnesium Sulphate (ACTOMgSO4) Collaborative Group (2003) Effect of Magnesium Sulfate Given for Neuroprotection Before Preterm Birth: A Randomized Controlled Trial. JAMA, 290, 2669-2676.
https://doi.org/10.1001/jama.290.20.2669
[5]  Doyle, L.W., Crowther, C.A., Middleton, P., Marret, S. and Rouse, D. (2009) Magnesium Sulphate for Women at Risk of Preterm Birth for Neuroprotection of the Fetus. Cochrane Database of Systematic Reviews, No. 1, Article No. CD004661.
https://doi.org/10.1002/14651858.CD004661.pub3
[6]  Marret, S., Marpeau, L., Beenichou, J., Follet-Bouhamed, C., Camboni, G., Astruc, D., et al. (2008) Effect of Magnesium Sulphate on Mortality and Neurological Morbidity in Preterm Infants Less than 33 Weeks of Age at Two Years: Results of the Prospective Multicentre Placebo-Controlled PREMAG Trial. Gynécologie Obstétrique & Fertilité, 36, 278-288.
https://doi.org/10.1016/j.gyobfe.2008.01.012
[7]  Launey, M. (2017) Evaluation of the Protocol of Fetal Neuroprotection by Magnesium Sulfate before 33 Weeks of Amenorrhea, at the CHU de Nantes: Retrospective Study from August 1, 2014 to December 31, 2015 [Mémoire gynecol obstet]. University of Nantes, Nantes, 63.
[8]  Mokuolu, O.A., Suleiman, B., Adesiyun, O. and Adeniyi, A. (2010) Prevalence and Determinants of Pre-Term Deliveries in the University of Ilorin Teaching Hospital, Ilorin, Nigeria. Pediatric Reports, 2, e3.
https://doi.org/10.4081/pr.2010.e3
[9]  Hounkponou, N.F.M., Tonato Bagman, A., Ahouingnan, A.Y., Gbevo, S., Laourou, H., Vodouhe, M., et al. (2017) Frequency and Factors Associated with Premature Deliveries at the Borgou Alibori University and Departmental Hospital in Benin. European Scientific Journal, 13, 427-435.
[10]  Muchie, K.F., Lakew, A.M., Teshome, D.F., Yenit, M.K., Sisay, M.M., Mekonnen, F.A., et al. (2020) Epidemiology of Preterm Birth in Ethiopia: Systematic Review and Meta-Analysis. BMC Pregnancy and Childbirth, 20, Article No. 574.
https://doi.org/10.1186/s12884-020-03271-6
[11]  National Institute of Statistics and Demography (2015) Tableau de bord démographique. Ministry of Economy and Finance, Burkina Faso, 61.
[12]  Chang, H.H., Larson, J., Blencowe, H., Spong, C.Y., Howson, C.P., Cairns-Smith, S., et al. (2013) Preventing Preterm Births: Analysis of Trends and Potential Reductions with Interventions in 39 Countries with Very High Human Development Index. Lancet, 381, 223-234.
https://doi.org/10.1016/S0140-6736(12)61856-X
[13]  Ferrero, D.M., Larson, J., Jacobsson, B., Di Renzo, G.C., Norman, J.E., Martin, J.N., et al. (2016) Cross-Country Individual Participant Analysis of 4.1 Million Singleton Births in 5 Countries with Very High Human Development Index Confirms Known Associations but Provides No Biologic Explanation for 2/3 of All Preterm Births. PLOS ONE, 11, e0162506.
https://doi.org/10.1371/journal.pone.0162506
[14]  McPherson, J.A., Rouse, D.J., Grobman, W.A., Palatnik, A. and Stamilio, D.M. (2014) Association of Duration of Neuroprotective Magnesium Sulfate Infusion with Neonatal and Maternal Outcomes. Obstetrics & Gynecology, 124, 749-755.
https://doi.org/10.1097/AOG.0000000000000467
[15]  Chang, Y.K., Tseng, Y.T. and Chen, K.T. (2020) The Epidemiologic Characteristics and Associated Risk Factors of Preterm Birth from 2004 to 2013 in Taiwan. BMC Pregnancy and Childbirth, 20, Article No. 201.
https://doi.org/10.1186/s12884-020-02903-1
[16]  Miranda, M.L., Edwards, S.E. and Myers, E.R. (2011) Adverse Birth Outcomes among Nulliparous vs. Multiparous Women. Public Health Reports, 126, 797-805.
https://doi.org/10.1177/003335491112600605
[17]  Kacerovsky, M., Musilova, I., Khatibi, A., Skogstrand, K., Hougaard, D.M., Tambor, V., et al. (2012) Intraamniotic Inflammatory Response to Bacteria: Analysis of Multiple Amniotic Fluid Proteins in Women with Preterm Prelabor Rupture of Membranes. The Journal of Maternal-Fetal & Neonatal Medicine, 25, 2014-2019.
https://doi.org/10.3109/14767058.2012.671873
[18]  Palacio, M., Cobo, T., Bosch, J., Filella, X., Navarro-Sastre, A., Ribes, A., et al. (2009) Cervical Length and Gestational Age at Admission as Predictors of Intra-Amniotic Inflammation in Preterm Labor with Intact Membranes. Ultrasound in Obstetrics & Gynecology, 34, 444-447.
https://doi.org/10.1002/uog.6437
[19]  Millochau, J.C., Marret, S., Oden, S. and Verspyck, E. (2016) Overview of the Use of Magnesium Sulphate for Neuroprotective Purposes at the Rouen University Hospital. Gynécologie Obstétrique & Fertilité, 44, 446-449.
https://doi.org/10.1016/j.gyobfe.2016.05.008
[20]  Gibbins, K.J., Browning, K.R., Lopes, V.V., Anderson, B.L. and Rouse, D.J. (2013) Evaluation of the Clinical Use of Magnesium Sulfate for Cerebral Palsy Prevention. Obstetrics & Gynecology, 121, 235-240.
https://doi.org/10.1097/AOG.0b013e31827c5cf8
[21]  Bouet, P.E., Brun, S., Madar, H., Baisson, A.L., Courtay, V., Gascoin-Lachambre, G., et al. (2015) Implementation of an Antenatal Magnesium Sulfate Protocol for Fetal Neuroprotection in Preterm Infants. Scientific Reports, 5, Article No. 14732.
https://doi.org/10.1038/srep14732
[22]  Marret, S., Marpeau, L., Zupan-Simunek, V., Eurin, D., Lévêque, C., Hellot, M.F., et al. (2007) Magnesium Sulphate Given before Very-Preterm Birth to Protect Infant Brain: The Randomised Controlled PREMAG Trial. BJOG, 114, 310-318.
https://doi.org/10.1111/j.1471-0528.2006.01162.x
[23]  Rouse, D.J., Hirtz, D.G., Thom, E., Varner, M.W., Spong, C.Y., Mercer, B.M., et al. (2008) A Randomized, Controlled Trial of Magnesium Sulfate for The prevention of Cerebral Palsy. New England Journal of Medicine, 359, 895-905.
https://doi.org/10.1056/NEJMoa0801187
[24]  Maged, M.C., Weiner, S.J. and Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network (2009) Effects of Antenatal Exposure to Magnesium Sulfate on Neuroprotection and Mortality in Preterm Infants: A Meta-Analysis. Obstetrics & Gynecology, 114, 354-364.
https://doi.org/10.1097/AOG.0b013e3181ae98c2
[25]  Crowther, C.A., Middleton, P.F., Voysey, M., Askie, L., Duley, L., Pryde, P.G., et al. (2017) Assessing the Neuroprotective Benefits for Babies of Antenatal Magnesium Sulphate: An Individual Participant Data Meta-Analysis. PLOS Medicine, 14, e1002398.
https://doi.org/10.1371/journal.pmed.1002398

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