术前超声引导下纳米炭精准定位在甲状腺微小病灶切除中的应用研究
Application of Precise Positioning of Preoperative Ultrasound-Guided Carbon Nanoparticles in Thyroidmicrolesion Resection

目的：探讨超声引导下纳米炭染色精准定位在甲状腺微小病灶切除手术中的应用价值。方法：收集我院经甲状腺超声检查发现的TI-RADS评价分类在III类及以上的微小病灶60例，随机将其分为实验组30例，和对照组30例。实验组采用超声引导下纳米炭染色精准定位后手术切除，对照组采用超声定位后手术切除。比较两种定位方法在完整切除病灶时间、术中出血量、一次精准切除病灶成功率以及切除组织量的差异。结果：实验组：完整切除病灶时间为(18.10 ± 5.81) min、术中出血量(20.30 ± 8.71) ml、切除组织重量(15.8 ± 6.6) g、一次精准切除病灶成功率96.6% (29/30)。对照组完整切除病灶时间为(18.10 ± 5.81) min、术中出血量(30.20 ± 10.70) ml、切除组织重量(28.50 ± 9.30) g、一次精准切除病灶成功率76.6% (23/30)。实验组患者手术中找到病灶时间显著少于对照组(P < 0.05)。实验组患者术中出血量、切除组织量方面和肿块定位成功率明显优于对照组(P < 0.05)。结论：与超声定位相比，超声引导下纳米炭染色精准定位可帮助术者在术中快速、准确地找甲状腺微小病灶，减少切除的甲状腺正常组织量，提高手术成功率。
Objective: To investigate the application value of ultrasound-guided preciselocalization of carbon nanoparticles in thyroid microfoci resection. Methods: Sixty patients with thyroid microlesions classified as class III or above by Tl-RADS were collected and randomly divided into experimental group (n = 30) and control group (n = 30). The experimental group was treated with ultrasound-guided carbon nanoscale staining for precise localization and surgical resection, while the control group was treated with ultrasound localization and surgical resection. The time of complete lesion resection, intraoperative blood loss, success rate of oneprecise lesion resection and the amount of tissue excised were compared between the two localization methods. Results: In the experimental group, the time of complete resection was (18.10 ± 5.81) min, the amount of intraoperative bloodloss was (20.30 ± 8.71) ml, the weight of resected tissue was (15.8 ± 6.6) g, and the success rate of one accurate resection was 96.6% (29/30). In the controlgroup, the time of complete resection was (18.10 ± 5.81) min, the amount of intraoperative blood loss was (30.20 ± 10.70) ml, the weight of resected tissue was (28.50 ± 9.30) g, and the success rate of one precise resection was 76.6% (23/30). The time to find the lesion in the experimental group was significantly shorter than that in the control group (P < 0.05). The intraoperative blood loss, the amount of resected tissue and the success rate of mass localization in the experimental group were significantly better than those in the control group (P< 0.05). Conclusions: Compared with ultrasound localization, ultrasound-guided preciselocalization of nano-carbon staining can help surgeons to quickly and accurately find thyroid microlesions during operation, reduce the amount of normal thyroid tissue removed, and improve the success rate of surgery.