全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...

肝外胆管切除在进展期胆囊癌根治术中临床价值的研究
Clinical Value of Extrahepatic Bile Duct Resection in Advanced Gallbladder Carcinoma

DOI: 10.12677/ACM.2022.1291209, PP. 8385-8389

Keywords: 进展期胆囊癌,肝外胆管,根治性手术,预后
Advanced Gallbladder Cancer
, Extrahepatic Bile Duct, Radical Surgery, Prognosis

Full-Text   Cite this paper   Add to My Lib

Abstract:

本文章的目的主要是探讨进展期胆囊癌根治术联合肝外胆管切除对患者长期预后的影响。方法:将青海大学附属医院肝胆胰外科2015年1月至2021年12月间收治的经病理诊断为进展期(≥T2期)胆囊癌患者,根据术中是否切除肝外胆管分为胆管切除组(n = 3)和胆管保留组(n = 9)。观察两组病人的临床病理学特征、并发症的发生率及两组患者的预后。结果显示:肝外胆管切除组的中位生存期为33个月,保留组的中位生存期8个月。两组病人生存率有可比性,但是无统计学差异,且肝外胆管切除组的生存率更高。
The purpose of this article is to investigate the long-term prognosis of patients with advanced gallbladder cancer who underwent radical resection combined with extrahepatic bile duct resec-tion. Methods: Patients with advanced stage (≥T2 stage) gallbladder cancer who were admitted to the Department of Hepatobiliary and Pancreatic Surgery of Qinghai University Affiliated Hospital from January 2015 to December 2021 were divided into bile duct resection group (n = 3) and bile duct preservation group (n = 9). The clinicopathological characteristics, the incidence of complica-tions and the prognosis of the two groups of patients were observed. The results showed that the median survival time of extrahepatic bile duct resection group was 33 months, and the median sur-vival time of preservation group was 8 months. The survival rates of the two groups were compara-ble, but not statistically different, and the survival rate of the extrahepatic bile duct resection group was higher.

References

[1]  Boutros, C., Gary, M., Baldwin, K. and Somasundar, P. (2012) Gallbladder Cancer: Past, Present and an Uncertain Fu-ture. Surgical Oncology, 21, e183-e191.
https://doi.org/10.1016/j.suronc.2012.08.002
[2]  Wang, J.K., Ma, W.J., Wu, Z.R., et al. (2019) Is Combined Extra-Hepatic Bile-Duct Resection Justified for Advanced Gallbladder Carcinoma? Gastroenterology Report, 7, 426-433.
https://doi.org/10.1093/gastro/goz018
[3]  Wakai, T., Shirai, Y., Yokoyama, N., et al. (2003) Depth of Subserosal Invasion Predicts Long-Term Survival after Resection in Patients with T2 Gallbladder Carcinoma. Annals of Surgical Oncology, 10, 447-454.
https://doi.org/10.1245/ASO.2003.06.014
[4]  Bloechle, C., Izbicki, J.R., Passlick, B., et al. (1995) Is Radical Surgery in Locally Advanced Gallbladder Carcinoma Justified? The American Journal of Gastroenterology, 90, 2195-2200.
[5]  郑亚新, 钟明安, 胡海, 等. 肝外胆管切除在T3 T4胆囊癌根治术临床价值研究[J]. 中国实用外科杂志, 2008, 28(12): 1051-1054.
[6]  殷晓煜. 肝外胆管切除在胆囊癌根治性切除术中的应用与价值[J]. 中国实用外科杂志, 2016, 36(10): 1048-1050.
[7]  Shukla, P.J. and Barreto, S.G. (2010) Systematic Review: Should Routine Resection of the Extra-Hepatic Bile Duct Be Performed in Gallbladder Cancer? Saudi Journal of Gastroenterology, 216, 161-167.
https://doi.org/10.4103/1319-3767.65184
[8]  Igami, T., Ebata, T., Yokoyama, Y., et al. (2015) Combined Extra-hepatic Bile Duct Resection for Locally Advanced Gallbladder Carcinoma: Does It Work? World Journal of Surgery, 39, 1810-1817.
https://doi.org/10.1007/s00268-015-3011-y
[9]  Nishio, H., Ebata, T., Yokoyama, Y., et al. (2011) Gallbladder Cancer Involving the Extrahepatic Bile Duct Is Worthy of Resection. Annals of Surgery, 253, 953-960.
https://doi.org/10.1097/SLA.0b013e318216f5f3
[10]  Sakamoto, Y., Kosuge, T., Shimada, K., et al. (2006) Clinical Significance of Extrahepatic Bile Duct Resection for Advanced Gallbladder Cancer. Journal of Surgical Oncology, 94, 298-306.
https://doi.org/10.1002/jso.20585
[11]  Shimizu, Y., Ohtsuka, M., Ito, H., et al. (2004) Should the Extra-hepatic Bile Duct Be Resected for Locally Advanced Gallbladder Cancer? Surgery, 136, 1012-1017.
https://doi.org/10.1016/j.surg.2004.04.032
[12]  Choi, S.B., Han, H.J., Kim, W.B., et al. (2013) Surgical Strategy for T2 and T3 Gallbladder Cancer: Is Extrahepatic Bile Duct Resection Always Necessary? Langenbeck’s Archives of Surgery, 398, 1137-1144.
https://doi.org/10.1007/s00423-013-1120-3

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133