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精子形态与复发性流产相关性的研究进展
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Abstract:
复发性流产的病因是复杂和多样的，其中多数病因不甚明确，部分诊疗措施仍然存在着争议，严重危害了诸多育龄期女性的身心健康。目前关于其病因的研究主要集中在女性因素方面，从男性角度研究复发性流产的报道较少，但妊娠是男女两性配子的结合，其中的男性因素也不容忽视，精子形态是精液参数分析中的重要组成部分，是评估男性精液质量和生育能力的重要指标。精子形态表现出对精子功能的潜在影响，并可能影响男性生殖能力，进而影响胚胎发育，诱发复发性流产。本文就目前国内外复发性流产与男性精子形态相关的研究现状进行综述，旨在为预防复发性流产发生以及为其治疗方向提供参考依据。
The etiology of recurrent abortion is complex and diverse; most of the reasons are not very clear; some therapeutic measures are still controversial, and seriously harm the physical and mental health of many women of reproductive age. The current research into the causes of its factors are mainly concentrated in women, and research report of recurrent miscarriage from the perspective of male is less; as the pregnancy is the union of male and female gametes, the male factors also do not allow to ignore, which mainly include genetic factors, immune factors, infection factors, semen parameters, age, occupational exposure, lifestyle, diet and drugs. Among them, sperm morphology is an important part of semen parameter analysis and an important index to evaluate male semen quality and fertility. Sperm morphology shows potential influence on sperm function, and may af-fect male reproductive ability, further affect embryo development, and induce recurrent abortion. This article reviews the research status of recurrent abortion and male sperm morphology at home and abroad in order to provide a reference for the prevention of recurrent abortion and its treat-ment direction.
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