Expectant Management of Preterm Ruptured Membranes before 34 Gestational Weeks at the University Hospital of Kinshasa, a Tertiary Referral Hospital in the Democratic Republic of Congo
Premature Rupture of Membranes (PROM)with the resulting prematurity remains a major public health issue in the Democratic Republic of Congo (DRC). This study aimed
to assess expectant management of PPROM before 34 weeks at the university
hospital of Kinshasa. We conducted a retrospective analysis of expectantly
managed PROM before 34 weeks between January 2008 and December 2018.Maternal and fetal outcomes
were collected, and all data were analyzed using the SPSS 23.0 software. Of the
113 patients included in the study, 2.6% were diagnosed with PROM before 34
weeks. We observed prolongation of the pregnancy
duration; the median latency period was eight days, and the average
gestational age at delivery of 32.85 ± 2.5 weeks. Chorioamnionitis (23%),
severe oligoamnios (7%), and acute fetal distress (4%) were complications
observed during the latency period. In the postpartum period, endometritis
(6.2%), neonatal jaundice (39.8%), anemia (25.7%), ulcerative necrotizing enterocolitis (6.2%), cerebromeningeal hemorrhage
(5.3%), and acute respiratory distress syndrome (4.4%) were
complications observed. The risk of infection during the latency period was
significantly associated with irregular (P = 0.045) or lack (P =
0.006) antenatal care (ANC) attendances and
C-Reactive Protein(CRP)
results < 6 (P = 0.013). The risk of neonatal death was significantly
associated to infection during the latency period (P =
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