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乳腺癌术后多年合并新发结节病一例并文献复习
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Abstract:
目的:探讨乳腺癌术后多年合并新发结节病的临床表现、诊断方法、检查结果及治疗方案。方法:对济宁市第一人民医院肿瘤科收治的1名乳腺癌术后多年合并新发结节病的患者进行病例分析并复习相关文献。结果:本例患者最终诊断为乳腺癌术后多年合并新发早期结节病,治疗上给予随访观察即可。结论:恶性肿瘤患者复查随访时,若发现多发淋巴结肿大、肺结节或者其他部位出现新生肿物时,应尽可能取得病理学诊断,以与第二原发肿瘤或良性疾病相鉴别。
Objective: To investigate the clinical manifestations, diagnostic methods, examination results and treatment of new sarcoidosis after many years of postoperative breast cancer. Methods: A patient with new sarcoidosis who was admitted to the Department of Oncology of Jining First People’s Hos-pital for many years after breast cancer surgery was analyzed and relevant literatures were re-viewed. Results: The patient was finally diagnosed as early sarcoidosis complicated by breast cancer for many years after surgery, and follow-up observation was sufficient. Conclusion: If multiple lym-phadenopathy, pulmonary nodules or neoplasms are found in patients with malignant tumor dur-ing follow-up, pathological diagnosis should be obtained as far as possible to distinguish them from the second primary tumor or benign disease.
[1] | Spagnolo, P., Rossi, G., Trisolini, R., et al. (2018) Pulmonary Sarcoidosis. The Lancet Respiratory Medicine, 6, 389-402.
https://doi.org/10.1016/S2213-2600(18)30064-X |
[2] | 王玲, 黄靖, 陈楠. 复发缓解型神经结节病1例[J]. 中国神经精神疾病杂志, 2020, 46(1): 39-40. |
[3] | Grunewald, J., Spagnolo, P., Wahlstrom, J., et al. (2015) Immunogenet-ics of Disease-Causing Inflammation in Sarcoidosis. Clinical Reviews in Allergy & Immunology, 49, 19-35. https://doi.org/10.1007/s12016-015-8477-8 |
[4] | Pawate, S., Moses, H. and Sriram, S. (2009) Presentations and Outcomes of Neurosarcoidosis: A Study of 54 Cases. QJM, 102, 449-460. https://doi.org/10.1093/qjmed/hcp042 |
[5] | Sung, H., Ferlay, J., Siegel, R.L., et al. (2021) Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: A Cancer Journal for Clinicians, 71, 209-249.
https://doi.org/10.3322/caac.21660 |
[6] | Waks, A.G. and Winer, E.P. (2019) Breast Cancer Treatment: A Review. JAMA, 321, 288-300.
https://doi.org/10.1001/jama.2018.19323 |
[7] | Arroyo-Crespo, J.J., Arminan, A., Charbonnier, D., et al. (2019) Characterization of Triple-Negative Breast Cancer Preclinical Models Provides Functional Evidence of Metastatic Pro-gression. International Journal of Cancer, 145, 2267-2281.
https://doi.org/10.1002/ijc.32270 |
[8] | Li, X., Yang, J., Peng, L., et al. (2017) Triple-Negative Breast Cancer Has Worse Overall Survival and Cause-Specific Survival than Non-Triple-Negative Breast Cancer. Breast Cancer Research and Treatment, 161, 279-287.
https://doi.org/10.1007/s10549-016-4059-6 |
[9] | Al-Mahmood, S., Sapiezynski, J., Garbuzenko, O.B., et al. (2018) Metastatic and Triple-Negative Breast Cancer: Challenges and Treatment Options. Drug Delivery and Translational Re-search, 8, 1483-1507.
https://doi.org/10.1007/s13346-018-0551-3 |
[10] | Chen, M.L., Ma, Z.S., Cao, F.L., et al. (2020) Retroperitoneal Metastasis Synchronous with Brain and Mediastinal Lymph Nodes Metastasis from Breast Invasive Ductal Carcinoma as the First Site of Distant Metastasis: A Case Report and Review of Literature. International Journal of Clinical and Ex-perimental Pathology, 13, 1693-1697. |
[11] | 邹立新, 黄君瑶. 乳腺癌淋巴结转移病例分析及研究[J]. 医学信息, 2006(11): 1994-1995. |
[12] | Kamby, C. andersen, J., Ejlertsen, B., et al. (1991) Pattern of Spread and Progression in Re-lation to the Characteristics of the Primary Tumour in Human Breast Cancer. Acta Oncologica, 30, 301-308.
https://doi.org/10.3109/02841869109092375 |
[13] | Sobel, J.M., Lai, R., Mallery, S., et al. (2005) The Utility of EUS-Guided FNA in the Diagnosis of Metastatic Breast Cancer to the Esophagus and the Mediastinum. Gastrointestinal Endoscopy, 61, 416-420.
https://doi.org/10.1016/S0016-5107(04)02759-2 |
[14] | Maccarone, M.T. (2019) FDG-PET Scan in Sarcoidosis: Clinical and Imaging Indications. Current Medical Imaging Reviews, 15, 4-9. https://doi.org/10.2174/1573405614666180626120832 |
[15] | Tana, M., di Carlo, S., Romano, M., et al. (2019) FDG-PET/CT Assessment of Pulmonary Sarcoidosis: A Guide for Internists. Current Medical Imaging Reviews, 15, 21-25. https://doi.org/10.2174/1573405614666180528101755 |
[16] | 马戈, 杨学东, 杨春山, 等. 18氟-脱氧葡萄糖PET/CT对结节病的影像学诊断分析[J]. 海军医学杂志, 2014(2): 106-107, 110. |
[17] | Mana, J. and Gamez, C. (2011) Molecular Imaging in Sarcoidosis. Current Opinion in Pulmonary Medicine, 17, 325-331.
https://doi.org/10.1097/MCP.0b013e3283480d36 |
[18] | Newman, L.S., Rose, C.S., Bresnitz, E.A., et al. (2004) A Case Control Etiologic Study of Sarcoidosis: Environmental and Occupational Risk Factors. American Journal of Res-piratory and Critical Care Medicine, 170, 1324-1330.
https://doi.org/10.1164/rccm.200402-249OC |
[19] | Valeyre, D., Prasse, A., Nunes, H., et al. (2014) Sarcoidosis. The Lancet, 383, 1155-1167.
https://doi.org/10.1016/S0140-6736(13)60680-7 |
[20] | Soto-Gomez, N., Peters, J.I. and Nambiar, A.M. (2016) Di-agnosis and Management of Sarcoidosis. American Family Physician, 93, 840-848. |
[21] | 杨芮一, 汪媛媛, 王艳菊, 等. 结节病肺内、外影像学特征及肺外累及预测因素的初探[J]. 临床肺科杂志, 2022, 27(2): 163-168. |
[22] | (1999) Statement on Sarcoidosis. Joint Statement of the American Thoracic Society (ATS), the European Respiratory Society (ERS) and the World Association of Sarcoidosis and Other Granulomatous Disorders (WASOG) Adopted by the ATS Board of Directors and by the ERS Executive Committee, February 1999. American Journal of Respiratory and Critical Care Medicine, 160, 736-755. |
[23] | Gerke, A.K. (2020) Treatment of Sarcoidosis: A Multidisciplinary Approach. Fron-tiers in Immunology, 11, Article ID: 545413. https://doi.org/10.3389/fimmu.2020.545413 |