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肺动脉高压于高原地区的研究现状
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Abstract:
我国是世界上高原面积最大的国家，越来越多的人因为工作或旅游等各种原因进入高原，一部分人因为无法适应高原特殊的环境会导致一系列头痛、嗜睡、疲劳和抑郁等症状甚至疾病。长期慢性低压缺氧是高原肺动脉高压(High altitude pulmonary hypertension, HAPH)的主要原因，HAPH是多种高原疾病的基础，导致右心功能不全和右心衰竭，甚至全心衰竭，具有较高的致残率和病死率，高原复杂的环境，仍需寻求更为优化的治疗方法及个体化治疗方式。本文阐述肺动脉高压于高原地区的研究现状。
China is the world’s largest plateau area of the country, more and more people because of work or tourism and other reasons into the plateau, part of the people because they can not adapt to the special environment of the plateau will lead to a series of headaches, lethargy, fatigue and depres-sion and other symptoms or diseases. Long-term chronic hypoxia is the main cause of pulmonary arterial hypertension at high altitude, and high altitude pulmonary hypertension is the basis of various altitude diseases, leading to right heart dysfunction and right heart failure, or even whole heart failure, with high disability rate and mortality. In the complex environment at high altitude, more optimized treatment and individual treatment methods are still needed. This paper reviews the research status of pulmonary arterial hypertension in plateau area.
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