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腹内压监测对危重病人肠内营养并发症影响的Meta分析
Effect of Intra-Abdominal Pressure Monitoring on Enteral Nutrition Complications in Critically Ill Patients: A Meta-Analysis

DOI: 10.12677/NS.2022.113061, PP. 366-375

Keywords: 肠内营养，危重病人，腹内压，Meta分析，并发症
Enteral Nutrition, Critically Ill Patients, Intra-Abdominal Pressure, META Analysis, Complications

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Abstract:

目的：系统评价腹内压监测对危重病人肠内营养并发症的干预效果。方法：系统检索PubMed、Embase、Web of Science、Cochrane library、中国知网(CNKI)、中国生物医学文献数据库(CBM)、万方数据库、维普中文科技期刊数据库(VIP)关于腹内压监测对危重病人肠内营养并发症影响的文献。检索时限为建库至2021年9月31日，两名研究人员独立完成文献筛选和质量评价后，通过RevMan5.3软件进行Meta分析。结果：共纳入10篇随机对照试验，Meta分析结果显示，腹内压监测可以降低患者腹泻(RR = 0.53, 95% CI: 0.42~0.66, P < 0.01)、腹胀(RR = 0.38, 95% CI: 0.26~0.57, P < 0.01)、呕吐(RR = 0.44, 95% CI: 0.33~0.59, P < 0.01)、肠鸣音减少或消失(RR = 0.52, 95% CI: 0.34~0.80, P < 0.01)、胃肠道出血(RR = 0.60, 95% CI: 0.39~0.92, P = 0.02)，减少患者住院时间(MD = ？4.88, 95% CI: ？7.08~？2.69, P < 0.01)、机械通气时间(MD = ？2.77, 95% CI: ？4.44~？1.10, P < 0.01)，降低APACHE-II评分(MD = ？5.08, 95% CI: ？7.44~？2.71, P < 0.01)。结论：现有证据表明，腹内压监测有助于降低危重患者腹泻、腹胀、呕吐、肠鸣音减弱或消失、胃肠道出血发生率；减少危重患者住院时间、机械通气时间，降低APACHE-II评分，但还需要更多高质量研究佐证研究结果。
Objective: To systematically evaluate the effect of intra-abdominal pressure monitoring on enteral nutrition complications in critically ill patients. Methods: Literatures concerning the effect of intra-abdominal pressure monitoring on enteral nutritional complications in critically ill patients were searched in these databases, including PubMed, Web of Science, EMbase, Cochrane library, CNKI, WanFang, CBM and VIP from inception to 31 September 2019. Meta analysis was performed by using RevMan 5.3 software. Results: A total of 10 randomized

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