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甲状腺微小乳头状癌术前诊断的研究进展
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Abstract:
甲状腺微小乳头状癌(papillary thyroid microcarcinoma，PTMC)早期易发生淋巴结转移，增加了肿瘤复发的风险，是影响患者预后的独立危险因素，且影响手术方式及术后综合方案的制定，因此早期发现及诊断对其具有重要意义。常用的术前诊断方法包括超声、超声造影、超声引导下细针穿刺活检(US-FNAB)、CT等，BRAF基因检测作为近几年新出现的检查手段，很大程度上提高了PTMC的术前诊断率。本文对不同的术前诊断方法作一综述，为临床合理选择辅助检查提供参考。
Papillary thyroid microcarcinoma (PTMC) is prone to lymph node metastasis in the early stage, which increases the risk of tumor recurrence, is an independent risk factor affecting the prognosis of patients, and affects the mode of operation and the formulation of postoperative comprehensive plan, so early detection and diagnosis are of great significance. The commonly used preoperative diagnosis methods include ultrasound, contrast-enhanced ultrasound, ultrasound-guided fine nee-dle biopsy (US-FNAB), CT and so on. As a new examination method in recent years, BRAF gene de-tection has greatly improved the preoperative diagnosis rate of PTMC. This article reviews different preoperative diagnostic methods in order to provide reference for clinical reasonable selection of auxiliary examination.
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