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胆汁酸水平与急性缺血性脑卒预后的相关性
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Abstract:
血清总胆汁酸既往多用于肝脏疾病诊断，近年来研究发现许多疾病如高血压、糖尿病、冠心病、脑血管疾病等患者的血清总胆汁酸水平都发生变化。已有一些研究证明胆汁酸通过多种机制参与糖脂代谢和脑卒中急性期炎症反应等多个方面。作者基于最新文献对胆汁酸可能对急性缺血性脑卒中患者产生神经保护的机制和临床预后进行了综述，可以为这个领域提供参考。
Serum total bile acid was mainly used for the diagnosis of liver diseases in the past. In recent years, studies have found that the serum total bile acid levels of patients with many diseases such as hy-pertension, diabetes, coronary heart disease, cerebrovascular diseases and other diseases have changed. Some studies have shown that bile acids participate in glycolipid metabolism and inflam-matory responses in the acute phase of stroke through a variety of mechanisms. Based on the latest literature, the authors reviewed the possible neuroprotective mechanisms and clinical prognosis of bile acids in patients with acute ischemic stroke, which could provide reference for this field.
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