Introduction:Cardiac amyloidosis is a rare and under-diagnosed
disease. The objective of this study was to collect cases of cardiac amyloidosis
in patients hospitalized in the cardiology department of the Centre Hospitalier
Intercommunal Alençon-Mamers (CHICAM). Patients and Methods: This was a
retrospective descriptive study of the records of patients diagnosed with
cardiac amyloidosis. The study took place in the cardiology department of the
CHICAM over 12 months (from January 1, 2020 to December 31, 2020).We included the files of
patients in whom the diagnosis of cardiac amyloidosis was confirmed on the
basis of clinical, echocardiographic, biological, scintigraphic and cardiac MRI
evidence. Results: Seven patients were included. The mean age was 86.71
years. Six men for one woman. Most of the patients were in heart failure. There
was one case of periorbital ecchymosis. Troponinemia was increased in three
patients, NTproBNP was always high with a mean of 1000ng/L. Cardiac echography showed a hyperbright septum
in four cases, concentric hypertrophy of the left ventricle with a mean
interventricular septum in diastole of 13.85mm. Six cases were senile transthyretin amyloidosis
(TTR), one case was mutated transthyretin amyloidosis (TTRm). Two cases of
death were noted. Conclusion: Cardiac amyloidosis has a poor prognosis
due to delayed diagnosis.
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