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儿童闭塞性细支气管炎的治疗进展
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Abstract:
儿童闭塞性细支气管炎(Bronchiolitis Obliterains, BO)是一种极其少见的不可逆的渐进性慢性阻塞性肺病，临床表现多为咳嗽、喘息、进行性呼吸困难、活动耐量下降，肺部啰音及哮鸣音。其发病机制尚不完全清楚。目前对于BO的治疗尚无明确标准，主要以对症支持治疗为主，治疗疗程长，疗效差，且相关报道多来源于国内外学者对成人及移植后BO患儿的研究，本文拟对最近5年与BO治疗相关的研究进行综述。
Bronchiolitis Obliterains (BO) in children is an extremely rare and irreversible progressive chronic obstructive pulmonary disease, which is characterized by cough, wheezing, progressive dyspnea, decreased activity tolerance, rales, and wheezing. Its pathogenesis is not fully understood. There is no clear standard for the treatment of BO, which is mainly symptomatic supportive treatment with long treatment course and poor efficacy. Moreover, most of the relevant reports are from studies on adults and children with BO after transplantation. This paper intends to review the research related to the treatment of BO in the recent 5 years.
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