Endometriosis
is an estrogen dependent gynecological disorder, which can occur throughout the
reproductive age of women, causing chronic pelvic pain, substantial morbidity,
and impaired fertility. It is clinically defined as the presence of ectopic
endometrium resulting in sustained inflammatory reaction. In India, about 29,000,000 women
suffer from endometriosis. Severe pelvic pain and recurrent endometriomas were
observed even after surgery. We have conducted aspirations totally in 110
patients in which most of the patients were suffering from Stage III & Stage
IV of endometriosis except for 7 patients for whom we have done as primary
therapy for endometriomas. Among 110 patients, 4 patients didn’t turn up for follow up after first aspiration. This
pilot study conducted with 110 patients in Ponni Hospital and Fertility
Research Centre, Madurai aimed to evaluate pregnancy outcome in 51 infertile
patients, and to alleviate pelvic pain, to restore a healthy sexual life and to
reduce the recurrence rate of Ovarian Endometriomas (OE) in 59 patients, who
did not seek fertility, After using the newer sclerosing agent Leuprolide with
Cefoperazone Sulbactam (LCS) under ultrasound guidance. This prospective pilot
study resulted in a highly significant achievement in pregnancy where 41
patients conceived out of 51 patients (80.39%) only 6 are in ongoing treatment.
Those who didn’t seek fertility were 59 of which 43 have completed family 13 have one child and 3 unmarried girls. 96.61% were relieved of pain
and recurrence and restored healthy sexual life, 2 are in ongoing treatment. We
have not encountered any adverse effects during this treatment.
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