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视网膜静脉阻塞合并黄斑水肿治疗现状
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Abstract:
视网膜静脉阻塞是多种原因导致视网膜静脉回流受阻,血液循环障碍的常见视网膜血管疾病,具有显著的致盲性。RVO根据阻塞的部位不同分为视网膜分支静脉阻塞(BRVO)、视网膜中央静脉阻塞(CRVO)。RVO患者视力下降的主要原因是黄斑水肿和新生血管。视网膜中央静脉研究小组(CVOS)提出格栅样激光光凝已经不是CRVO继发黄斑水肿(Macular Edema, ME)视力下降的一种有效的治疗方法。在过去的10几年中,几项主要的随机对照临床试验研究了RVO-ME新的治疗方法。本文旨在为RVO-ME的治疗提供现有的循证方法。
Retinal vein occlusions (RVO) are common retinal vascular disorders that have in common impaired venous return from the retinal circulation and blood circulation disorder, with the potential for significant vision-related morbidity. Retinal vein occlusions are classified as either branch retinal vein occlusion (BRVO) or central retinal vein occlusion (CRVO) based on the specific occlusion site. The main causes of vision loss in patients with RVO are associated with macular edema and neovascularization. The central vein occlusion study (CVOS) group demonstrated that grid laser photocoagulation is not an effective treatment for decreased vision due to CRVO-related macular edema. However, in the past ten years, several major randomized controlled clinical trials have investigated new therapeutic modalities for the treatment of macular edema secondary to RVO. This article aims to provide insight into current evidence based approaches to the treatment of RVO with macular edema.
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