外周神经损伤修复研究进展
Research Progress of Peripheral Nerve Injury Repair

DOI: 10.12677/BP.2021.114009, PP. 76-84

Keywords: 外周神经修复再生，施万细胞，营养因子，神经移植物
Peripheral Nerve Repair and Regen-eration, Schwann Cell, Neurotrophic Factor, Nerve Graft

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Abstract:

外周神经损伤是一种常见的损伤类疾病，目前治疗手段主要有显微外科手术、自体神经移植、异体神经移植和组织工程技术。目前治疗过程的主要瓶颈是供体神经的严重不足。现有研究指出影响修复过程因素主要包括：施万细胞、生长因子、细胞外基质等等。目前由于供体神经缺乏及外科手术精细度限制，组织工程技术结合了种子细胞、营养因子及支架材料，使得长间隙及粗大神经受损患者的康复具有可行性。我们相信随着科技发展，外周神经损伤类疾病的治疗与康复终会取得良好的临床效果。
There are four main therapies to cure peripheral nerve injury, which is a common injury disease, microsurgery, autologous nerve graft, nerve allograft and tissue engineering technology. The main block of current treatment process is the serious shortage of donor nerves. Existing research points out that the main factors affecting the repair process include: Schwann cells, growth factors, extracellular matrix, etc. At present, due to the lack of donor nerves and the limitation of surgical precision, tissue engineering technology combines seed cells, nutrient factors and scaffold materials, making the rehabilitation of patients with long gaps and large nerve damage feasible. We believe that with the development of science and technology, the treatment and rehabilitation of peripheral nerve injury diseases will eventually achieve good clinical results.

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