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保留膀胱颈的经尿道前列腺电切与标准术式的疗效比较
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Abstract:
目的:比较保留膀胱颈的TURP与标准TURP的疗效。方法:研究选取2019年6月~2020年6月因前列腺增生于我院行经尿道前列腺电切术(transurethral resection of prostate, TURP)的患者137例,根据是否保留膀胱颈分为实验组(保留膀胱颈的TURP) 58例和对照组(标准TURP) 79例。比较两组的围手术期指标,术后6个月的国际前列腺症状评分(international prostatic symptom score, IPSS)、最大尿流率(maximum urinary flow rate, Qmax)和包括逆行射精在内的并发症发生率。结果:两组在手术时间、留置导尿管时间、血红蛋白下降、住院时间等方面差异无统计学意义。术后随访6个月两组IPSS评分与最大尿流率亦无明显差异。实验组逆行射精发生率明显低于对照组(32.8% vs 77.2%, P < 0.001),但尿路梗阻、尿失禁、膀胱颈挛缩等并发症两组无明显差异。结论:与标准的TURP相比,保留膀胱颈的TURP在减少术后逆行射精率方面提供了更令人满意的临床结果。
Objective: To compare the efficacy of bladder neck preserving TURP with standard TURP. Methods: 137 patients receiving transurethral resection of prostate due to prostate hyperplasia in our hospital from June 2019 to June 2020 were selected. According to whether the bladder neck was preserved or not, the patients were divided into experimental group (TURP with preserved bladder neck) 58 cases and control group (standard TURP) 79 cases. Perioperative indicators, international prostatic symptom score (IPSS), maximum urine flow rate (Qmax), and incidence of complications including retrograde ejaculation were compared between the two groups. Results: There was no significant difference between the two groups in operation time, catheterization time, hemoglobin decrease and hospital stay. There was no significant difference in IPSS score and Qmax between the two groups after 6 months follow-up. The incidence of retrograde ejaculation in the experimental group was significantly lower than that in the control group (32.8% vs 77.2%, P < 0.001), but there were no significant differences in urinary tract obstruction, urinary incontinence, bladder neck contracture and other complications between the two groups. Conclusions: Compared with standard TURP, bladder neck sparing TURP provided a more satisfactory clinical outcome in reducing postoperative retrograde ejaculation rates.
[1] | Berry, S.J., Coffey, D.S., Walsh, P.C. and Ewing, L.L. (1984) The Development of Human Benign Prostatic Hyperplasia with Age. The Journal of Urology, 132, 474-479. https://doi.org/10.1016/S0022-5347(17)49698-4 |
[2] | Zhu, B.S., Jiang, H.C. and Li, Y. (2016) Impact of Urethral Catheterization on Uroflow during Pressure-Flow Study. Journal of International Medical Research, 44, 1034-1039. |
[3] | Unnikrishnan, R., Almassi, N. and Fareed, K. (2017) Benign Prostatic Hyperplasia: Evaluation and Medical Management in Primary Care. Cleveland Clinic Journal of Medicine, 84, 53-64. https://doi.org/10.3949/ccjm.84a.16008 |
[4] | Peng, M., Yi, L. and Wang, Y. (2016) Photoselective Vaporization of the Prostate vs Plasmakinetic Resection of the Prostate: A Randomized Prospective Trial with 12-Month Follow-Up in Mainland China. Urology, 87, 161-165.
https://doi.org/10.1016/j.urology.2014.08.038 |
[5] | Besiroglu, H. and Ozbek, E. (2017) Letter to the Editor Regarding the Article “The Effects of Statins on Benign Prostatic Hyperplasia in Elderly Patients with Metabolic Syndrome”. World Journal of Urology, 35, 177-178.
https://doi.org/10.1007/s00345-016-1844-0 |
[6] | Thomas, A.W., Cannon, A., Bartlett, E., Ellis-Jones, J. and Abrams, P. (2005) The Natural History of Lower Urinary Tract Dysfunction in Men: Minimum 10-Year Urodynamic Follow-Up of Untreated Bladder Outlet Obstruction. BJU International, 96, 1301-1306. |
[7] | Qu, M., Zhu, F., Chen, H., Lian, B., Jia, Z., Shi, Z., Li, J., Wang, Y., Sun, Y. and Gao, X. (2019) Palliative Transurethral Resection of the Prostate in Patients with Metastatic Prostate Cancer: A Prospective Study of 188 Patients. Journal of Endourology, 33, 570-575. https://doi.org/10.1089/end.2019.0108 |
[8] | Yeni, E., Unal, D., Verit, A. and Gulum, M. (2002) Minimal Transurethral Prostatectomy plus Bladder Neck Incision versus Standard Transurethral Prostatectomy in Patients with Benign Prostatic Hyperplasia: A Randomised Prospective Study. Urologia Internationalis, 69, 283-286. https://doi.org/10.1159/000066127 |
[9] | Kusljic, S., Aneja, J. and Manias, E. (2017) Incidence of Complications in Men Undergoing Transurethral Resection of the Prostate. Collegian, 24, 3-9. https://doi.org/10.1016/j.colegn.2015.07.001 |
[10] | Rassweiler, J., Teber, D., Kuntz, R. and Hofmann, R. (2006) Complications of Transurethral Resection of the Prostate (TURP)—Incidence, Management, and Prevention. European Urology, 50, 969-979.
https://doi.org/10.1016/j.eururo.2005.12.042 |
[11] | Asimakopoulos, A.D., Mugnier, C., Hoepffner, J.L., Piechaud, T. and Gaston, R. (2012) Bladder Neck Preservation during Minimally Invasive Radical Prostatectomy: A Standardised Technique Using a Lateral Approach. BJU International, 110, 1566-1571. https://doi.org/10.1111/j.1464-410X.2012.11604.x |
[12] | Ronzoni, G. and De Vecchis, M. (1998) Preservation of Anterograde Ejaculation after Transurethral Resection of Both the Prostate and Bladder Neck. British Journal of Urology, 81, 830-833.
https://doi.org/10.1046/j.1464-410x.1998.00658.x |
[13] | Liao, J., Zhang, X., Chen, M., Li, D., Tan, X., Gu, J., Hu, S. and Chen, X. (2019) Transurethral Resection of the Prostate with Preservation of the Bladder Neck Decreases Postoperative Retrograde Ejaculation. Wideochirurgia I Inne Techniki Maloinwazyjne, 14, 96-101. https://doi.org/10.5114/wiitm.2018.79536 |
[14] | Elkhodair, S., Parmar, H.V. and Vanwaeyenbergh, J. (2005) The Role of the IPSS (International Prostate Symptoms Score) in Predicting Acute Retention of Urine in Patients Undergoing Major Joint Arthroplasty. Surgeon, 3, 63-65.
https://doi.org/10.1016/S1479-666X(05)80063-0 |
[15] | Gosling, J.A., Dixon, J.S. and Jen, P.Y. (1999) The Distribution of Noradrenergic Nerves in the Human Lower Urinary Tract. A Review. European Urology, 36, 23-30. https://doi.org/10.1159/000052314 |
[16] | Gosling, J.A. (1986) The Distribution of Noradrenergic Nerves in the Human Lower Urinary Tract. Clinical Science, 70, 3s-6s. https://doi.org/10.1042/cs070s003 |
[17] | He, L.Y., Zhang, Y.C., He, J.L., Li, L.X., Wang, Y., Tang, J., Tan, J., Zhong, K., Tang, Y.X. and Long, Z. (2016) The Effect of Immediate Surgical Bipolar Plasmakinetic Transurethral Resection of the Prostate on Prostatic Hyperplasia with Acute Urinary Retention. Asian Journal of Andrology, 18, 134-139. https://doi.org/10.4103/1008-682X.157395 |
[18] | Barazani, Y., Stahl, P.J., Nagler, H.M. and Stember, D.S. (2012) Management of Ejaculatory Disorders in Infertile Men. Asian Journal of Andrology, 14, 525-529. https://doi.org/10.1038/aja.2012.29 |
[19] | Gil-Vernet, J.M., Alvarez-Vijande, R., Gil-Vernet, A. and Gil-Vernet, J.M. (1994) Ejaculation in Men: A Dynamic Endorectal Ultrasonographical Study. British Journal of Urology, 73, 442-448.
https://doi.org/10.1111/j.1464-410X.1994.tb07612.x |
[20] | Gray, M., Zillioux, J., Khourdaji, I. and Smith, R.P. (2018) Contemporary Management of Ejaculatory Dysfunction. Translational Andrology and Urology, 7, 686-702. https://doi.org/10.21037/tau.2018.06.20 |
[21] | Lourenco, T., Shaw, M., Fraser, C., MacLennan, G., N’Dow, J. and Pickard, R. (2010) The Clinical Effectiveness of Transurethral Incision of the Prostate: A Systematic Review of Randomised Controlled Trials. World Journal of Urology, 28, 23-32. https://doi.org/10.1007/s00345-009-0496-8 |