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Medical Diagnosis 2021
早期复发性流产血栓前状态诊治的中西医研究进展
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Abstract:
复发性流产(recurrent spontaneous abortion, RSA)是生殖育龄期女性的常见疾病，现代医学认为血栓前状态(prethrombotic state, PTS)所致复发性流产是研究热点。西医治疗大多以抗凝及免疫治疗为基本治法，但不良反应和风险较大。文献显示中医药治疗副作用相对较小，而疗效较为显著，易被患者接受。本文对早期复发性流产血栓前状态诊治的中西医研究进展进行概述。
Recurrent spontaneous abortion (RSA) is a common disease in women of reproductive age. Modern medicine believes that recurrent spontaneous abortion (PTS) caused by prethrombotic state (PTS) is a research hotspot. Western medicine treatment is mostly based on anticoagulation and immu-notherapy, but adverse reactions and the risk are greater. The literature shows that the side effects of traditional Chinese medicine treatment are relatively small, and the curative effect is more obvi-ous, and it is easy to be accepted by patients. This article summarizes the research progress of Chi-nese and Western medicine in the diagnosis and treatment of prethrombotic state in early recur-rent miscarriage.
| [1] | Practice Committee of the American Society for Reproductive Medicine (2012) Evaluation and Treatment of Recurrent Pregnancy Loss: A Committee Opinion. Fertility and Sterility, 98, 1103-1111.
https://doi.org/10.1016/j.fertnstert.2012.06.048 |
| [2] | 张建平, 吴晓霞. 血栓前状态与复发性流产[J]. 中国实用妇科与产科杂志, 2007, 23(12): 917-920. |
| [3] | 张建平, 林其德, 李大金, 等. 复发性流产的诊断与治疗[J]. 现代妇产科进展, 2006, 15(7): 486. |
| [4] | Kutten, W.H. and Tripletr, D.A. (2006) Thrombophilias and Recurrent Pregnancy Loss. Seminars in Reproductive Medicine, 24, 54-66. https://doi.org/10.1055/s-2006-931801 |
| [5] | Quenby, S., Mountfield, S., et al. (2005) Antiphospholipid Antibodies Prevent Extravillous Trophoblast Differentiation. Fertility and Sterility, 83, 691-698. https://doi.org/10.1016/j.fertnstert.2004.07.978 |
| [6] | 张运丽, 郭婧婧, 金燕, 等. 反复自然流产患者封闭抗体检测的临床意义[J]. 实用预防医学, 2009, 16(6): 1917-1918. |
| [7] | 黄丹云, 叶平. 肾虚血瘀在复发性流产中的临床意义[J]. 吉林中医药, 2010, 30(1): 24-25. |
| [8] | 谢春光, 蓝肇熙, 杜联, 等. 当归芍药散对痛经患者的血液流变性及PGF2a水平的影响[J]. 中西医结合杂志, 1990, 10(7): 410. |
| [9] | 罗振宇, 柴冬宁. 复发性流产的免疫学研究进展[J]. 中华临床医师杂志(电子版), 2010, 4(12): 2489-2492. |
| [10] | 李昭荣, 韩香, 吕海侠, 等. 蜕膜自然杀伤细胞与不明原因反复自然流产的关系[J]. 生殖医学杂志, 2005, 14(2): 68. |
| [11] | Pierangeli, S.S., Gir-ardi, Q., Vega-Ostertag, M., Liu, X., Espinola, R.Q. and Salmon, J. (2005) Requirement of Activation of Complement C3 and C5 for Antiphospholipid Antibody-Mediated Thrombophilia. Arthritis & Rheumatology, 52, 2120-2124. https://doi.org/10.1002/art.21157 |
| [12] | Stagnaro-Green, A., Roman, S.H., Cobin, R.H., et al. (1990) Detection of At-Risk Pregnancy by Means of Highly Sensitive Assays for Thyroid Autoantibodies. JAMA, 264, 1422-1425. https://doi.org/10.1001/jama.264.11.1422 |
| [13] | Van den Boogaard, E., Vissenberg, R.L., et al. (2011) PH Signifi-cance of (Sub)clinical Thyroid Dysfunction and Thyroid Autoimmunity before Conception and in Early Pregnancy: A Systematic Review. Human Reproduction Update, 17, 605-619. https://doi.org/10.1093/humupd/dmr024 |
| [14] | 吴嵩龄, 倪斌, 殷兆初, 等. 自然流产与5种病原体宫内感染关系的研究[J]. 中国优生与遗传杂志, 2001, 9(1): 72-73. |
| [15] | 张玉珍. 中医妇科学[M]. 北京: 中国中医药出版社, 2011: 219-224. |
| [16] | 杜冠华, 李军. 益气化瘀中药治疗高凝状态自身免疫型复发性自然流产临床研究[J]. 新中医, 2013, 45(1): 92-94. |
| [17] | 尤昭玲, 王若光, 李军, 等. 益气化瘀法对胎儿宫内发育迟缓患者子宫动脉、脐动脉血流影响的研究[J]. 中国中医药科技, 2000, 7(5): 321. |
