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酶蛋白质中8类二级结构的识别
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Abstract:
酶是一种具有催化功能的蛋白质，研究酶蛋白质中的二级结构对研究酶的结构及功能有重要作用。本文从酶蛋白质序列出发，以位点氨基酸和20种氨基酸n-gap 2肽组分为参数，首次将矩阵打分的方法用于酶蛋白质中8类二级结构的识别，预测总精度Q8最高达到61.4%。
Enzymes are a kind of protein that has catalytic function. The study of secondary structures in en-zymes plays an important role in the structure and function of enzymes. Based on enzyme protein sequence information, amino acids of sites and n-gap dipeptide composition of twenty amino acids were selected as parameters. Scoring matrix method was first applied to the identification of 8-state secondary structure in enzymes protein. The prediction accuracy of Q8 reached 61.4%.
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