Introduction:A newborn is preterm when it is born before 37 weeks of amenorrhoea.
Preterm births account for 11.1% of live births worldwide, 60% of which are in
South Asia and sub-Saharan Africa. Preterm birth is the leading cause of neonatal
mortality and the second leading cause of mortality in children under 5 years
of age. The aim of this study was to investigate prematurity in the neonatology
unit of the Mali Hospital. Materials and Methods: This was a
cross-sectional, descriptive study from January 2012 to December 2015 of
premature newborns from 28 to 36 weeks of amenorrhea in the neonatology unit of
Mali Hospital. Results: From January 2012 to December 2015, we recorded
1692 inpatient newborns, including 614 preterm newborns, a frequency of 36.29%.
The sex ratio was 1.43 in favor of boys. The average age of the mothers was
23.9 years with a minimum of 15 and a maximum of 47 years. The majority were
housewives (92.7%). The pregnancy was poorly monitored in 51.8% of the mothers.
The average gestational age was 32.9 days with extremes of 25 and 36 days. The
most frequent mode of delivery was vaginal delivery (93.2%), with late
prematurity in 51.5%, moderate prematurity (24.4%), extreme prematurity (18.7%)
and very premature (5.4%). The mean birth weight was 1464 g with a standard
deviation of 485 g and 2751 g. Prematurity was associated with neonatal
infection in 49.4% of newborns, perinatal anoxia (13.9%) and hypotrophy (2.6%).
The most frequent maternal risk factors were fever (83.4%), twinship (38.9%)
and high blood pressure (8.6%). The average length of hospitalization was 9.75
days with extremes of 0 and 68 days. We recorded a cure rate of 57.7%, a death
rate of 35.7% and a dropout rate of 6.7%. Conclusion: Prematurity is
frequent in the neonatology unit of the Mali Hospital. We observed a high
frequency among women of extreme age and low socio-economic and educational
level. In our study we also noted a high mortality rate proportional to
gestational age.
References
[1]
OMS. Incidence mondiale de la naissance avant terme: Revue systématique de la mortalité et de la morbidité maternelle.
[2]
Torchin, H. and Ancel, P.-Y. (2016) épidémiologie et facteurs de risque de la prématurité. Journal de Gynécologie Obstétrique et Biologie de la Reproduction, 45, 1213-1230. https://doi.org/10.1016/j.jgyn.2016.09.013
[3]
Cohen-Solal, E. and Cravello, L. (2010) évolution de la prématurité—Evolution of preterm birth. 4.
Torchin, H., Ancel, P.-Y., Jarreau, P.-H. and Goffinet, F. (2015) épidémiologie de la prématurité: Prévalence, évolution, devenir des enfants. Journal de Gynécologie Obstétrique et Biologie de la Reproduction, 44, 723-731.
https://doi.org/10.1016/j.jgyn.2015.06.010
[10]
Dicko-Traoré, F., Sylla, M., Traoré, Y., Traoré, A., Diall, H., Diakité, A.A., et al. (2014) Unité de néonatologie de référence nationale du Mali: état des lieux. Sante Publique (Bucur), 26, 115-121. https://doi.org/10.3917/spub.137.0115
[11]
Kouakou, C., Dainguy, M. and Kouadio, E. (2016) Facteurs de risque de deces du premature dans un service de reference a abidjan. Revue Internationale des Sciences Médicales, 18, 35-41.
[12]
Sow, A., Gueye, M., Boiro, D., Ndongo, A.A., Coundoul, A.M., Diouf, S., et al. (2018) Prématurité: épidémiologie et facteurs étiologiques dans une maternité de Dakar (Sénégal). Journal de Pédiatrie et de Puériculture, 31, 91-95.
https://doi.org/10.1016/j.jpp.2018.02.001
[13]
Zini, M.E. and Omo-Aghoja, L.O. (2019) Clinical and Sociodemographic Correlates of Preterm Deliveries in Two Tertiary Hospitals in Southern Nigeria. Ghana Medical Journal, 53, 20-28. https://doi.org/10.4314/gmj.v53i1.4
[14]
Diouf, F.N. (2017) Aspects socio-démographiques, épidémiologiques, cliniques et pronostiques de la prématurité dans l’unité de néonatologie de l’hôpital d’enfant Albert Royer de Dakar/Sénégal. Rev Afr Malgache Rech Sci Santé, 4, 19-23.
[15]
Mbayo, F.I., Nsenga, Y.B., Lupitshi, G.K., Nyemba, K.T., Mpingisha, C.M., Kambala, J.B., et al. (2020) The Determinants of Premature Birth during the Year 2018 at the General Reference Hospital of Malemba in the Democratic Republic of Congo. The Pan African Medical Journal, 37, 30.
https://doi.org/10.11604/pamj.2020.37.30.25205
[16]
Lejeune, C. (2008) Précarité et prématurité. Journal de Pédiatrie et de Puériculture, 21, 344-348. https://doi.org/10.1016/j.jpp.2008.09.008
[17]
Belinga, E., Foumane, P., Dohbit, S.J., Ngo Um, E.M., Kiyeck, D.K. and Mboudou, E.T. (2017) Pronostic des références obstétricales à l’Hôpital Gynéco-Obstétrique et Pédiatrique de Yaoundé (HGOPY). The Pan African Medical Journal, 28, 301.
https://doi.org/10.11604/pamj.2017.28.301.10773
[18]
El Masnaoui, N., Barkat, A., Hatou, F., Kabiri, M. and Lamdouar Bouazzaoui, N. (2009) Facteurs impliqués dans la mortalité périnatale des nouveau-nés issus de grossesses multiples de haut rang. Journal de Pédiatrie et de Puériculture, 22, 193-196. https://doi.org/10.1016/j.jpp.2009.05.005
[19]
Amri, F., Fatnassi, R., Negra, S. and Khammari, S. (2008) Prise en charge du nouveau-né prématuré. Journal de Pédiatrie et de Puériculture, 21, 227-231.
https://doi.org/10.1016/j.jpp.2008.04.019
[20]
Sow, A., Gueye, M., Boiro, D., Ndongo, A.A., Coundoul, A.M., Diouf, S., et al. (2018) Prématurité: épidémiologie et facteurs étiologiques dans une maternité de Dakar (Sénégal). Journal de Pédiatrie et de Puériculture, 31, 91-95.
[21]
Dainguy, M., Folquet, A. and Akaffou, M. (2011) Suivi ambulatoire du premature la premiere annee de vie au service de pediatrie du chu de cocody. Le Mali médical, 26, 25-29.
[22]
Butali, A., Ezeaka, C., Ekhaguere, O., Weathers, N., Ladd, J., Fajolu, I., et al. (2016) Characteristics and Risk Factors of Preterm Births in a Tertiary Center in Lagos, Nigeria. The Pan African Medical Journal, 24, Article No. 1.
https://doi.org/10.11604/pamj.2016.24.1.8382
[23]
Castaigne, V., Picone, O. and Frydman, R. (2005) Accouchement du prématuré. EMC—Gynécologie-Obstétrique, 2, 354-363.
https://doi.org/10.1016/j.emcgo.2005.09.001