A Study on Pre-Induction Cervical Ripening with PGE2 Vaginal Tablet One (3 mg) vs. Half (1.5 mg) in Low Risk Multi Parous Mothers at 40 Weeks of Gestation
Backgrounds: Induction of labor is a common practice. In women with immature cervix, PGE2 is commonly used for
pre-induction. We hypothesized that PGE2 1.5mg may be equally effective to PGE2 3mg in multiparous women for labor induction. The
present effort was an attempt to compare the efficacy and effects of
pre-induction cervical ripening with PGE2 3mg vs. 1.5mg in multi-parous mothers (2nd and 3rd Pregnancy)
at 40 weeks.Methods: A double-blind
References
[1]
WHO (2018) Recommendations: Induction of Labour at or Beyond Term. World Health Organization, Geneva.
[2]
WHO (2017) Managing Complication in Pregnancy and Childbirth: A Guide for Midwives and Doctors. World Health Organization, Geneva.
[3]
Huszar, G., Cabrol, D. and Naftolin, F. (2020) The Relationship between Myometrial Contractility and Cervical Maturation in Pregnancy and Labor. Medicine, Dentistry, Nursing & Allied Health, 2, 10 p.
[4]
Alfirevic, Z., Baxter, J., Calder, A., Green, J., Markham, C., Shehata, H., McCormick, C. and Hill, S.S. (2008) Nice clinical guidelines, Induction of Labor. RCOG Press, London.
[5]
Batista, L., Chung, J.H., Lagrew, D.C. and Wing, D.A. (2007) Complications of Labor Induction among Multiparous Women in a Community Based Hospital System. American Journal of Obstetrics & Gynaecology, 197, 241.
[6]
Bishop, E.H. (1964) Pelvic Scoring for Elective Induction. Obstetrics and Gynaecology, 24, 266-267.
[7]
Hughey, M.J., Mcelin, T.W. and Bird, C.C. (1976) An Evaluation of Pre Induction Scoring Systems. Obstetrics and Gynaecology, 48, 635-641.
[8]
Sahar, H., Katariina, L., Erik, F., Niveen, M.E., Abu-Rmeileh, H.Y., Ali-Masri, M.Z., Kaled, Z., Åse, V. and Khaled, M.I. (2019) Induction of Labor among Singleton Pregnancies in Six Palestinian Governmental Hospitals: A Population-Based Cohort Study. International Journal of Women’s Health, 11, 597-605.
https://doi.org/10.2147/IJWH.S215781
[9]
Joscha, R., Roberta, R., Yuan, J.P., Sven, S., Eva, H., Michael, H.E. and Frank, L. (2014) Prostaglandin E2 Labour Induction with Intravaginal (Minprostin) versus Intracervical (Prepidil) Administration at Term: Randomized Study of Maternal and Neonatal Outcome and Patient’s Perception Using the Osgood Semantic Differential Scales. BioMed Research International, 2014, Article ID: 682919.
https://doi.org/10.1155/2014/682919
[10]
Author (2008) NICE clinical guideline 70: Induction of Labour.
https://www.nice.org.uk/guidance/CG70
[11]
Bahar, A.M., Archibong, E.I., Zaki, Z.M. and Mahfouz, A.A. (2003) Induction of Labour Using Low and High Dose Regimens of Prostaglandin E2 Vaginal Tablets. East African Medical Journal, 80, 51-55. https://doi.org/10.4314/eamj.v80i1.8666
[12]
Deurenberg, P., Deurenberg, M. and Guricci, S. (2002) Asians Are Different from Caucasians and from Each Other in Their Body Mass Index/Body Fat Percent Relationship. Obesity Reviews, 3, 141-146.
https://doi.org/10.1046/j.1467-789X.2002.00065.x
[13]
Goldenberg, R.L., McClure, E.M., Bhattacharya, A.M.H.S., Groat, T.D. and Stahl, P.J. (2009) Women’s Perceptions Regarding the Safety of Births at Various Gestational Ages. Obstetrics and Gynaecology, 114, 1254-1258.
https://doi.org/10.1097/AOG.0b013e3181c2d6a0
[14]
Michael, Y., Haglund, B., Henry, N. and Magnus, W. (1998) Fetal & Neonatal Mortality in the Post Term Pregnancy, the Impact of Gestational Age. American Journal of Obstetrics and Gynaecology, 178, 726-731.
https://doi.org/10.1016/S0002-9378(98)70482-X
[15]
Roshini, R., Philip, S. and Mark, P. (2004) Does Gestation Vary by Ethnic Group? A London Based Study of over 122000 Pregnancies with Spontaneous Onset of Labour. The International Journal of Epidemiology, 33, 107-113.
https://doi.org/10.1093/ije/dyg238
[16]
Rayburn, W.F., et al. (1992) Intravaginal Controlled Release Prostaglandin E2 Pessary for Cervical Ripening & Initiation of Labour at Term. Clinical Obstetrics and Gynaecology, 79, 374-379. https://doi.org/10.1097/00006250-199203000-00009
[17]
Hefni, M.A. and Lewis, G.A. (1980) Induction of Labour with Vaginal PGE2 3mg Pessaries. British Journal of Obstetrics and Gynaecology, 87, 199-202.
https://doi.org/10.1111/j.1471-0528.1980.tb04518.x
[18]
Pez, V., Deruelle, P., Kyheng, M., Boyon, C., Clouqueur, E. and Garabedian, C. (2018) Cervical Ripening and Labor Induction: Evaluation of Single Balloon Catheter Compared to Double Balloon Catheter and Dinoprostone Insert. Gynecol Obstet Fertil Senol, 46, 570-574.
[19]
Rashmi, V., Jacqueline, N. and Lynne, C. (1981) Induction of Labour with Vaginal PGE2 3mg Pessaries. Journal of Obstetrics and Gynaecology, 2, 65-70
[20]
Houghton, D.J. (1982) An Evaluation of the Bishops Scoring System in Relation to a Method of Induction of Labour by Intra Vaginal Prostaglandin. Postgraduate Medical Journal, 58, 403-407.
[21]
Sanchez, R. and Dirk, E. (1988) Gaudier, Labour Induction with PGE1 Misoprostol Compared with Dinoprostone Vaginal Insert. Obstetrics and Gynaecology, 91, 319-483.