In our medical practice, in particular obstetrics, it is difficult to
change certain consolidated dogmas, but the necessity and the current situation
of our obstetrical exercise pushed us to find new technical supports, to make
the exercise of our specialty as stripped of pitfalls as possible. Our work is
summarized in a prospective comparative study, aimed at evaluating the existence
or not of a difference between the administration of oxytocin just before the
hysterotomy in a cesarean section and its administration after fetal
extraction. We used a set of criteria to include patients in our study. This
study took place over a period of one year (2020) in the Mother and Child
regional center, in Meknes Imperial city, Morocco, involving a total number of
364 patients. With a group A comprising 176 patients 48% (176/364) who received
oxytocin just before the hysterotomy and a group B of 188 patients 52%
(188/364) who received it classically after fetal extraction. The difference
was very significant as detailed in the article. Conclusion: the very
convincing results of our study and the difference between the two groups,
allowed us to demonstrate the effectiveness of our process and to endorse its
use in our routine practice, with the perspective of conducting a prospective
randomized study on a larger series.
Viviani, D. and Stoop, R. (2008) Opposite Effects of Oxytocin and Vasopressin on the Emotional Expression of the Fear Response. Progress in Brain Research, 170, 207-218. https://doi.org/10.1016/S0079-6123(08)00418-4
[3]
Martin-Du Pan, R.C. (2012) Oxytocin: The Hormone of Love, Trust and Social Bond. Clinical Use in Autism and Social Phobia. Revue Médicale Suisse, 8, 627-630.
[4]
Ondrasek, N. (2017) Oxytocin. In: Vonk, J. and Shackelford, T.K., Eds., Encyclopedia of Animal Cognition and Behavior, Springer International Publishing AG, Berlin, 1-10.
[5]
Pascal Santi. L’ocytocine déroutante hormone de l’amour dans le monde du 5 septembre 2018, suppl. Science et Médecine.
[6]
Lee, H.-J., Macbeth, A.H., Pagani, J.H. and Young, W.S. (2009) Oxytocin: The Great Facilitator of Life. Progress in Neurobiology, 88, 127-151.
https://doi.org/10.1016/j.pneurobio.2009.04.001
[7]
Broad, K.D., Curley, J.P. and Keverne, E.B. (2006) Mother-Infant Bonding and the Evolution of Mammalian Social Relationships. Philosophical Transactions of the Royal Society B: Biological Sciences, 361, 2199-2214.
https://doi.org/10.1098/rstb.2006.1940
[8]
Numan, M. and Young, L.J. (2016) Neural Mechanisms of Mother-Infant Bonding and Pair Bonding: Similarities, Differences, and Broader Implications. Hormones and Behavior, 77, 98-112. https://doi.org/10.1016/j.yhbeh.2015.05.015
[9]
Blanc-Petitjean, P. (2013) Ocytocine de synthese et travail spontane. Etude avantapres la mise en place d’un protocole a l’hôpital Louis-Mourier. Gynecologie et obstetrique. dumas-00874840.
[10]
Warkus, T., Denys, A., Hohlfeld, P. and Gerber, S. (2005) Priseen Charge de l’hémorragie du Post-Partum. Revue Médicale Suisse, 1, 30784.
[11]
Ozier, Y. (1998) The Paradox of Disseminated Intravascular Coagulation. Annales Françaises d’Anesthésie et de Réanimation, 17, 18s-22s.
https://doi.org/10.1016/S0750-7658(98)80101-9
[12]
Recommandations pour la pratique clinique: Les hémorragies du post-partum élaborées par le Collège national des gynécologues et obstétriciens français.
[13]
Hidar, S., et al. (2004) The Effect of Placental Removal Method at Cesarean Delivery on Perioperative Hemorrhage: A Randomized Clinical Trial ISRCTN 49779257. European Journal of Obstetrics & Gynecology and Reproductive Biology, 117, 179-182.
https://doi.org/10.1016/j.ejogrb.2004.03.014
[14]
Abdelmounaim, L.G., Biougnach, N., Rabea, B., Driss, H., Adil, T. and Said, L. (2020) A New Surgical Way to Face Postpartum Hemorrhage. Open Journal of Obstetrics and Gynecology, 10, 1147-1155. https://doi.org/10.4236/ojog.2020.1090108
[15]
Subtil, D., Sommé, A., Ardiet, E. and Depret-Mosser, S. (2004) Postpartum Hemorrhage: Frequency, Cosequences in Terms of Health Status, and Risk Factors before Delivery. Journal de Gynécologie Obstétrique et Biologie de la Reproduction, 33, 9-16. https://doi.org/10.1016/S0368-2315(04)96644-6
[16]
Parant, O., Guerby, P. and Bayoumeu, F. (2004) Spécificités obstétricales et anesthésiques de la prise en charge d’une hémorragie du post-partum (HPP) associée à la césarienne. Journal de Gynécologie Obstétrique et Biologie de la Reproduction, 43, 1104-1122. https://doi.org/10.1016/j.jgyn.2014.10.004
[17]
Recommandations pour la pratique clinique: Les hémorragies du post-partum; élaborées par le Collège national des gynécologues et obstétriciens français en 2014.
