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迷走神经刺激治疗难治性抑郁症的研究进展
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Abstract:
迷走神经刺激技术经历了植入式迷走神经向经皮迷走神经刺激技术方向的发展。本文系统综述了近年来迷走神经刺激术在治疗抑郁症特别是在治疗难治性抑郁症方面的研究进展，分别从迷走神经刺激的发展，VNS治疗TRD的作用机制研究进展，VNS治疗TRD的有效性研究，VNS治疗TRD研究的不足和展望，从这个四个方面进行综述总结，希望为临床工作者使用VNS治疗技术，提供一定的参考，并为将来VNS的发展进行展望。笔者相信，随着研究的升入和检测技术的提高和相关学者的努力探索，相信未来i-VNS在治疗TRD方面将会取得更大突破，i-VNS这一疗法也可能会在临床上得到更多的应用。
The technique of vagus nerve stimulation has experienced the development from implantable va-gus nerve to percutaneous vagus nerve stimulation. In recent years were reviewed in this paper, system the vagus nerve stimulation in the treatment of depression, especially in the progress of treatment-resistant depression, respectively from the development of the vagus nerve stimulation; the mechanism of action of VNS therapy for TRD research progress TRD; the VNS therapy effective-ness for TRD research; the VNS therapy for TRD research of deficiencies and prospects. This paper summarizes the four aspects, hoping to provide some references for clinical workers to use VNS treatment technology, and prospect the development of VNS in the future. The author believes that with the advancement of research and the improvement of detection technology and the efforts of relevant scholars, i-VNS will make a greater breakthrough in the treatment of TRD in the future, and the treatment of i-VNS may be applied more in clinical practice.
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