Postpartum hemoglobinuria (PPH) is a sporadic noninfectious syndrome
which normally seen in bovine around the world. PPH is most commonly affecting
high-productive cows and buffaloes during the early pregnancy and early
lactation period. PPH stands as a
serious threat to the dairy cattle and buffaloes in Afghanistan, Pakistan, and India, affecting a considerable number of
animals every year. It is characterized by hemoglobinuria, intravenous hemolysis, severe anemia, and death due to anemia and hypoxia. However, the
exact mechanism of the mentioned illness is not completely understood. Lots of
comprehensive studies have been done and/or still are in progress in order to
find the exact causes of intravascular hemolysis that is responsible for
hemoglobinuria in the mentioned disease. But, hypophosphatemia in the high
productive milking cows during the early stage of milk production is widely
confident to be
associated with PPH. In different parts of the world, many risk factors had been reported to be associated with
PPH. Decreasing the level of phosphorous in blood serum, interrupted the
phospholipid layers of red blood cells resulting in hemoglobinuria, a decrease in milk
production, anorexia, and the death of animals in the
cause if remained untreated. Urinalysis and hematology findings are the most
commonly suitable diagnostic tools for this disease. Lots of studies have been
suggesting that injection of sodium acid phosphate along with important
minerals and supportive therapy with anti-oxidants
can be used as the therapeutic protocol for the management o
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