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慢性失眠共病OSAHS的研究进展
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Abstract:
在睡眠领域慢性失眠和阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea-hypopnea syn-drome, OSAHS)是最常见的两大类疾病，近年来研究发现慢性失眠和OSAHS相互作用影响，可引起更严重的睡眠结构紊乱、焦虑抑郁症状、认知功能下降和躯体化症状的发生，严重者会导致心脑血管疾病甚至猝死的发生，因此对慢性失眠共病OSAHS的及时筛查和诊治尤为必要，但由于两者的共病关系对治疗方案的选择成为了新的挑战，本综述对慢性失眠共病OSAHS的流行病学特点、共病影响机制、临床特征表现和治疗方案选择等方面进行阐述。
Chronic insomnia and obstructive sleep apnea-hypopnea syndrome (OSAHS) are the two most common diseases in the field of sleep. In recent years, studies have found that the interaction be-tween chronic insomnia and OSAHS can cause more serious sleep structure disorders, anxiety and depression symptoms, cognitive decline and somatization symptoms. In severe cases, it can lead to cardiovascular and cerebrovascular diseases and even sudden death. Therefore, it is necessary to screen, diagnose and treat OSAHS in time, but because of the relationship between the two diseases, the choice of treatment options has become a new challenge. This review describes the epidemio-logical characteristics, comorbidity mechanism, clinical features and treatment options of chronic insomnia comorbid OSAHS.
| [1] | Ito, E. and Inoue, Y. (2015) The International Classification of Sleep Disorders, Third Edition. American Academy of Sleep Medicine. Includes Bibliographies and Index. Nihon Rinsho, 73, 916-923. |
| [2] | Javaheri, S. and Redline, S. (2017) Insomnia and Risk of Cardiovascular Disease. Chest, 152, 435-444.
https://doi.org/10.1016/j.chest.2017.01.026 |
| [3] | Hong, S.O., Chen, Y.F., Jung, J., et al. (2017) Hypoglossal Nerve Stimulation for Treatment of Obstructive Sleep Apnea (OSA): A Primer for Oral and Maxillofacial Surgeons. Maxillofa-cial Plastic and Reconstructive Surgery, 39, 27.
https://doi.org/10.1186/s40902-017-0126-0 |
| [4] | Guilleminault, C., Eldridge, F.L. and Dement, W.C. (1973) In-somnia with Sleep Apnea: A New Syndrome. Science, 181, 856-858. https://doi.org/10.1126/science.181.4102.856 |
| [5] | Glidewell, R.N., Renn, B.N., Roby, E., et al. (2014) Predictors and Patterns of Insomnia Symptoms in OSA before and after PAP Therapy. Sleep Medicine, 15, 899-905. https://doi.org/10.1016/j.sleep.2014.05.001 |
| [6] | Krakow, B., Melendrez, D., Ferreira, E., et al. (2001) Prevalence of Insomnia Symptoms in Patients with Sleep-Disordered Breathing. Chest, 120, 1923-1929. https://doi.org/10.1378/chest.120.6.1923 |
| [7] | Ong, J.C. and Crisostomo, M.I. (2013) The More the Merrier? Working towards Multidisciplinary Management of Obstructive Sleep Apnea and Comorbid Insomnia. Journal of Clini-cal Psychology, 69, 1066-1077.
https://doi.org/10.1002/jclp.21958 |
| [8] | Zhang, Y., Ren, R., Lei, F., et al. (2019) Worldwide and Regional Preva-lence Rates of Co-Occurrence of Insomnia and Insomnia Symptoms with Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis. Sleep Medicine Reviews, 45, 1-17. https://doi.org/10.1016/j.smrv.2019.01.004 |
| [9] | Mysliwiec, V., Matsangas, P., Baxter, T., et al. (2014) Comorbid Insomnia and Obstructive Sleep Apnea in Military Personnel: Cor-relation with Polysomnographic Variables. Military Medicine, 179, 294-300.
https://doi.org/10.7205/MILMED-D-13-00396 |
| [10] | Philip, P., Bioulac, S., Altena, E., et al. (2018) Specific In-somnia Symptoms and Self-Efficacy Explain CPAP Compliance in a Sample of OSAS Patients. PLoS ONE, 13, e0195343. https://doi.org/10.1371/journal.pone.0195343 |
| [11] | Sweetman, A., Lack, L., Lambert, S., et al. (2017) Does Comorbid Obstructive Sleep Apnea Impair the Effectiveness of Cognitive and Behavioral Therapy for Insomnia? Sleep Medicine, 39, 38-46.
https://doi.org/10.1016/j.sleep.2017.09.003 |
| [12] | Leiter, J.C., Knuth, S.L. and Bartlett, D.J. (1985) The Effect of Sleep Deprivation on Activity of the Genioglossus Muscle. The American Review of Respiratory Disease, 132, 1242-1245. |
| [13] | Bayliss, D.A., Viana, F., Talley, E.M., et al. (1997) Neuromodulation of Hypoglossal Motoneurons: Cellular and Developmental Mechanisms. Respiration Physiology, 110, 139-150. https://doi.org/10.1016/S0034-5687(97)00079-0 |
| [14] | Osman, A.M., Carter, S.G., Carberry, J.C., et al. (2018) Ob-structive Sleep Apnea: Current Perspectives. Nature and Science of Sleep, 10, 21-34. https://doi.org/10.2147/NSS.S124657 |
| [15] | Sweetman, A., Lack, L. and Bastien, C. (2019) Co-Morbid Insomnia and Sleep Apnea (COMISA): Prevalence, Consequences, Methodological Considerations, and Recent Randomized Con-trolled Trials. Brain Sciences, 9, 371.
https://doi.org/10.3390/brainsci9120371 |
| [16] | Ratnavadivel, R., Chau, N., Stadler, D., et al. (2009) Marked Reduc-tion in Obstructive Sleep Apnea Severity in Slow Wave Sleep. Journal of Clinical Sleep Medicine, 5, 519-524. https://doi.org/10.5664/jcsm.27651 |
| [17] | Gold, A.R., Gold, M.S., Harris, K.W., et al. (2008) Hypersomnolence, Insomnia and the Pathophysiology of Upper Airway Resistance Syndrome. Sleep Medicine, 9, 675-683. https://doi.org/10.1016/j.sleep.2007.08.013 |
| [18] | Umlauf, M.G., Chasens, E.R., Greevy, R.A., et al. (2004) Ob-structive Sleep Apnea, Nocturia and Polyuria in Older Adults. Sleep, 27, 139-144. https://doi.org/10.1093/sleep/27.1.139 |
| [19] | Balbo, M., Leproult, R. and Van Cauter, E. (2010) Impact of Sleep and Its Disturbances on Hypothalamo-Pituitary-Adrenal Axis Activity. International Journal of Endocrinology, 2010, Article ID: 759234. https://doi.org/10.1155/2010/759234 |
| [20] | Chotinaiwattarakul, W., O’Brien, L.M., Fan, L., et al. (2009) Fatigue, Tiredness, and Lack of Energy Improve with Treatment for OSA. Journal of Clinical Sleep Medicine, 5, 222-227. https://doi.org/10.5664/jcsm.27490 |
| [21] | Luyster, F.S., Buysse, D.J. and Strollo, P.J. (2010) Comorbid Insomnia and Obstructive Sleep Apnea: Challenges for Clinical Practice and Research. Journal of Clinical Sleep Medicine, 6, 196-204. https://doi.org/10.5664/jcsm.27772 |
| [22] | Chung, K.F. (2005) Insomnia Subtypes and Their Relationships to Daytime Sleepiness in Patients with Obstructive Sleep Apnea. Respiration, 72, 460-465. https://doi.org/10.1159/000087668 |
| [23] | Bjornsdottir, E., Janson, C., Sigurdsson, J.F., et al. (2013) Symptoms of Insomnia among Patients with Obstructive Sleep Apnea before and after Two Years of Positive Airway Pressure Treat-ment. Sleep, 36, 1901-1909.
https://doi.org/10.5665/sleep.3226 |
| [24] | Gooneratne, N.S., Gehrman, P.R., Nkwuo, J.E., et al. (2006) Consequenc-es of Comorbid Insomnia Symptoms and Sleep-Related Breathing Disorder in Elderly Subjects. Archives of Internal Medicine, 166, 1732-1738.
https://doi.org/10.1001/archinte.166.16.1732 |
| [25] | Smith, S., Sullivan, K., Hopkins, W., et al. (2004) Frequency of Insomnia Report in Patients with Obstructive Sleep Apnoea Hypopnea Syndrome (OSAHS). Sleep Medicine, 5, 449-456. https://doi.org/10.1016/j.sleep.2004.03.005 |
| [26] | Li, Z., Li, Y., Yang, L., et al. (2015) Characterization of Obstruc-tive Sleep Apnea in Patients with Insomnia across Gender and Age. Sleep and Breathing, 19, 723-727. https://doi.org/10.1007/s11325-015-1121-2 |
| [27] | 雷飞, 任蓉, 杜丽娜, 等. 失眠合并阻塞性睡眠呼吸暂停低通气综合征患者的夜间睡眠图结构特征[J]. 华西医学, 2016, 31(8): 1321-1324. |
| [28] | 叶静怡, 王彦婷, 毛丹丹, 等. 失眠伴阻塞性睡眠呼吸暂停患者睡眠特征结构分析[J]. 国际精神病学杂志, 2020, 47(5): 960-963. |
| [29] | Wang, S.H., Chen, W.S., Tang, S.E., et al. (2018) Benzodiazepines Associated with Acute Respiratory Failure in Patients with Obstructive Sleep Apnea. Frontiers in Pharmacology, 9, 1513. https://doi.org/10.3389/fphar.2018.01513 |
| [30] | Drab, D.L. (2003) The Relationship between Obstructive Sleep Ap-nea Syndrome and Insomnia: Implications for Treatment. |
| [31] | Wichniak, A., Wierzbicka, A., Walecka, M., et al. (2017) Effects of Antidepressants on Sleep. Current Psychiatry Reports, 19, 63. https://doi.org/10.1007/s11920-017-0816-4 |
| [32] | Aloia, M.S. (2011) Understanding the Problem of Poor CPAP Adherence. Sleep Medicine Reviews, 15, 341-342.
https://doi.org/10.1016/j.smrv.2011.04.002 |
| [33] | Lettieri, C.J., Shah, A.A., Holley, A.B., et al. (2009) Effects of a Short Course of Eszopiclone on Continuous Positive Airway Pressure Adherence: A Randomized Trial. Annals of Inter-nal Medicine, 151, 696-702.
https://doi.org/10.7326/0003-4819-151-10-200911170-00006 |
| [34] | Ong, J.C., Crawford, M.R., Dawson, S.C., et al. (2020) A Randomized Controlled Trial of CBT-I and PAP for Obstructive Sleep Apnea and Comorbid Insomnia: Main Outcomes from the MATRICS Study. Sleep, 43, zsaa041.
https://doi.org/10.1093/sleep/zsaa041 |
| [35] | Lack, L. and Sweetman, A. (2016) Diagnosis and Treatment of Insomnia Comorbid with Obstructive Sleep Apnea. Sleep Medicine Clinics, 11, 379-388. https://doi.org/10.1016/j.jsmc.2016.05.006 |
| [36] | Fung, C.H., Martin, J.L., Josephson, K., et al. (2016) Efficacy of Cognitive Behavioral Therapy for Insomnia in Older Adults with Occult Sleep-Disordered Breathing. Psychosomatic Medicine, 78, 629-639.
https://doi.org/10.1097/PSY.0000000000000314 |
| [37] | Sweetman, A., Lack, L., McEvoy, R.D., et al. (2020) Cognitive Behavioural Therapy for ？nsomnia Reduces Sleep Apnoea Severity: A Randomised Controlled Trial. ERJ Open Research, 6, 00161-2020.
https://doi.org/10.1183/23120541.00161-2020 |
