The comparison of two endometrial biopsy techniques in detection of endometrial pathologies

Objective: The purpose of this study is to compare the diagnostic performance of hysteroscopic endometrial biopsy (H/S) and probe curettage (P/C) in the diagnosis of endometrial pathologies. Material and Methods: Our study was conducted at a tertiary obstetrics and gynecology clinic between December 2010 and July 2011. In our prospective study, histopathological results of both biopsies with H/S and P/C applied to 83 patients admitted to our clinic for evaluation of endometrium, were examined and compared with combine procedure (H/S and P/C). Results: Histopathological results were as follows: endometrial polyps (48%), endometrial hyperplasia (13.2%), submucous myoma (4.8%), endometrial cancer (4.8%), and normal endometrial tissue (28.9%). Sensitivity values of biopsy with H/S versus biopsy with P/C for the endometrial polyp, submucous myoma, endometrial hyperplasia and endometrial cancer were found as 97.5% vs. %54,6, 100% vs.%25 , 75% vs. %100 and 63.6% vs. %100, respectively. Conclusion: H/S was apparently superior to P/C in diagnosis of focal lesions such as endometrial polyps and submucous myoma. We determined none of the interventions to be statistically superior to the other in diagnosis of diffuse lesions such as endometrial hyperplasia and endometrial cancer