Histomorphological diagnostic diffuculties in colon perforation

In this review, histomorphologic diagnostic difficulties were evaluated in cases that colon perforation was detected and partial/total colectomy was performed. Although it is not difficult to report histomorphologic findings of colon perforation within the clinical knowledge in the practice of pathology, the absence of characteristic findings in some cases may cause difficulties in diagnosis. Although clinical information is often sufficient for histological diagnosis, differential diagnosis difficulties are experienced in pathology practice, such as Crohn's, amebic colitis, and intestinal Beh？et's diseases