The Effects of Biotin Use in Multiple Sclerosis

Multiple sclerosis (MS) is the most common neurological disorder since the beginning of the 20th century and approximately 2.5 million patients with MS are estimated in the world. It is reported that MS is seen 1 in one thousand young adults in the United States and Europe. The epidemiological studies conducted in our country show that the prevalence of MS is 0.4-1 per thousand. Visual blur, diplopia, dysarthria, concentration-attention disorders, weakness in extremities, ataxia, fatigue, bladder problems are frequently listed as symptoms. Although genetic and environmental risk factors play an important role in pathophysiology, there is no specific pathogenesis for MS. Due to the fact that it is a rapidly progressive disease, studies on treatment options are continuing and suggestions for delaying the symptoms are presented. In recent years, topics are highlight on the biotin issue, to delay the progression of the disease and to improve the quality of life of individuals. In this review, it is aimed to evaluate the hypotheses about the ways of improvement in MS related dysfunctions of high dose biotin use and the results of the study in these subjects