Current approach to vitamin D insufficiency and deficiency

Vitamin D is a secosteroid hormone in adipose tissue which has a significant impact on the bone metabolism and serum calsium balance. Vitamin D deficiency and insufficiency associated with the incidence and severity of many autoimmune diseases including common cancers, infectious diseases, metabolic syndrome, hypertension, myocardial infarctions and increase of the risc of cardiovasculer illnesses, multipl sclerosis, rheumatoid arthritis and type 1 diabetes. Although there is no consensus on optimal level of vitamin D the most researches have accepted the level of 25(OH)D in the following order: the value above 30 ng/mL indicates competency, between 20-30 ng/mL indicates insufficiency, below 20 ng/mL indicates deficiency. In our country vitamin D deficiency is a common problem and it has a negative effects on cancer, systematic diseases, bone health therefore in our revieve we aimed to present the physiology of vitamin D in adults, define vitamin D deficiency and present the current approach in the treatment process