INVESTIGATION OF SOME HEMATOLOGICAL AND BIOCHEMICAL PARAMETERS OF RATS WERE GIVEN VACCINIUM MYRTILLUS (BLUEBERRY) EXTRACT

Aim: In this study, the differences in hematological and biochemical parameters were investigated in rats given Vaccinium myrtillus (blueberry) extract. Method: Biochemical parameters albumin (Alb), alkaline phosphatase (ALP), alanine aminotransferase (ALT), amylase (AMY), blood urea nitrogen (BUN), calcium (Ca), creatinine (CRE), potassium (K), sodium (Na), phosphorus (Phos), total bilirubin (TBIL), total protein (TP), fasting glucose (FG), total cholesterol (TC), and hematologic parameters such as WBC, LYM, MON, NEU, LY, MO, NE, RBC, HGB, HCT MCV, MCH, MCHC, RDW, PLT, PCT, MPV, PDW levels were measured. In the study, rats were used as animal material. The rats were separated into two groups, each of which included 10 rats. Ad libitum fed rats were subjected to the control group. In the group of blueberry extract for a period of 8 weeks of the experiment the rate of 20 mg/kg were mixed with drinking water. Results: Completion of the process of the experiment, after obtaining blood samples from the above parameters, creatinine: 0.48 from 0:41 to fell in value. MPV: 6.48 from 6.30 a, PDW: 33.40 from the 32.48 level have fallen. But no significant changes were observed outside of these parameters. Conclusion: As a result, there is a negative impact on blood parameters of blueberry on the contrary due to the significant decrease in the values of MPV and PDW, which is a risk factor for hardening of the arteries as a result of oxidative damage fragmented platelets sticking to the walls of arteries and reduce the risk of atherosclerosis be considered