Antibacterial Effects of Microencapsulated Probiotic and Synbiotics

The present study aims to evaluate the inhibition effect of microencapsulated probiotic culture with prebiotics against two different pathogen enterococci strain. Lactobacillus rhamnosus was used as probiotic, inulin and fructooligosaccharide (FOS) were used as prebiotics. Microencapsulation maintained with three different combinations as only probiotic culture, probiotic culture with inulin and probiotic culture with FOS. In addition, the effect of inulin and FOS on survival of L. rhamnosus was evaluated. L. rhamnosus was microencapsulated by the extrusion technique and its antibacterial effect on clinical vancomycin-susceptible Enterococcus faecalis (VSEF) and clinical vancomycin-resistant Enterococcus faecium (VREF) growth was determined. According to the obtained results, microencapsulated probiotic culture with prebiotic addition showed inhibition effect on VREF growth. Furthermore, it was found that the survival rate of the probiotic culture cells varied according to the prebiotic. It was determined that inulin was more efficient on L. rhamnosus cell viability than FOS