Optimization study for the determination of bisphenol A in thermal printing papers

In this study, a sensitive and accurate method for the quantitative determination of bisphenol A (BPA) in thermal printing paper was developed and validated. BPA was extracted from the thermal printing papers using acetonitrile- water. The effects of organic solvent concentration, extraction temperature and time, pH were investigated. Under the optimized conditions (acetonitrile:water 40:60, v/v, pH=7, 60 oC, 8 hours), the proposed method was applied to the determination of BPA in five types of thermal printing papers (receipt, POS receipt, hospital barcode, ATM receipt, flight ticket), and the concentration of BPA was found in the range of 8.91-10.27 mg g-1. Furthermore, spiked RSD % of BPA at 5 and 10 mg g-1was found to be 1.80 and 2.90, respectively