Primary and Collagen Supported Scaffold Healing in Rabbit Horizontal Meniscus Ripped Models

The aim of this study is to investigate the potential for improvement of the collagen scaffold in the repair of horizontal meniscus tears in the rabbit model. Mature 21 New Zealand white male rabbits weighing 2.5-3 kg were divided into 3 equal groups, with 7 animals in each group. The medial meniscus was anteriorly horizontal torn from the horn to the middle. In accordance with the study protocol, Group 1 (n=7); only the horizontal meniscus was tilted in the control group. Group 2 (n=7); horizontal meniscus rupture primer repair. Group 3; horizontal meniscus were repaired with a colloidal scaffold. All experimental animals were sacrificed at the end of the 12th week. 1/3 anterior area of medial meniscus was measured. Histological analysis of the tissues was performed with Ishida score consisting of three components. Surface area of meniscus in group I was significantly lower than group II (p<0.008) and group III (p<0.002). The quality of the group III was significantly higher than the other groups (p<0.001). In the tears of the avascular region, such as the horizontal meniscus tears, scaffolds and similar materials can provide better healing and meniscal function and function close to normal anatomic tissue