Patient with Type 1 Diabetes and Microalbuminuria

Abstract Diabetic kidney disease is one of the most common and serious chronic complications of type 1 diabetes. Microalbuminuria is one of the early findings of diabetic kidney disease and it is found to be associated with mortality. The abnormal increase of albumin excretion is due to microvascular lesions in glomerulicaused by long lasting hyperglycemia. The screening for microalbuminuria is recommended to be performed by measurement of urinary albumin to creatinineratio, after 5 years of diabetes diagnosis and repeated annually afterwards. Risk factors like long diabetes time, poor glycemic and blood pressure control, dyslipidemia and smoking increase the probability of overt diabetic kidney disease intype 1 diabetics with microalbuminuria. But the spontaneous regression of microalbuminuria to normoalbuminuria is also possible. The regulation of glycemiaand blood pressure, inhibition of renin-angiotensin-aldosterone-system and theavoidance of other risk factors are found to be effective in prevention or treatment of microalbuminuria