Evaluation of Helicobacter pylori prevalence in celiac disease

Background and Aims: Although studies have reported a protective role of Helicobacter pylori against celiac disease, some studies have shown an increased prevalence of Helicobacter pylori in celiac disease. We aimed to detect the prevalence of Helicobacter pylori at the time of the diagnosis of celiac disease and compared it with an age-matched control group in our clinic. Materials and Methods: In this study, 41 celiac and 82 control patients, with similar age and sex, who underwent an upper gastrointestinal endoscopy for dyspeptic symptoms were included. Results: Helicobacter pylori was detected in 20 (48.8%) of the 41 celiac patients and in 70 (85.4%) of the 82 control subjects. The prevalence of Helicobacter pylori was lower in celiac patients than in the general population. Conclusion: Multicenter studies including a larger number of patients are needed to assess the role of Helicobacter pylori in the pathogenesis of celiac disease