The usefulness of monocyte to high density lipoprotein cholesterol ratio in prediction for coronary artery ectasia

Aim: Monocyte count to high density lipoprotein cholesterol ratio (MHR) has been shown to be a useful inflammatory marker in patients with coronary artery disease. Hence, the aim of the study was to evaluate whether there is an association between coronary artery ectasia (CAE) and MHR. Material and methods: In this retrospective case-control study, a total of 5500 patients who underwent an elective coronary angiography between July 2013 and July 2016 were retrospectively screened. Of these patients, 150 (2.7%) patients were found to have an isolated CAE. The control group was consisted of 150 normal coronary artery patients who matched with this group in terms of age, gender, and body mass index. Results: The median value of MHR was found to be a statistically higher in patients with CAE (p<0.05). In multivariable analyses, MHR (OR: 1.71, 95% CI: 1.219-2.484, p=0.002) was found to be an independent predictor of CAE. Conclusion: We observed that MHR levels were higher in CAE patients when compared to healthy subjects. Our findings may indicate a common pathophysiological mechanism between CAE and coronary artery disease