Primary Splenic angiosarcoma a case report and literature review

Primary splenic angiosarcoma is a very aggressive neoplasm with poor prognosis due to its very high frequency of metastasis. The tumor cells exhibit a strong positivity for at least one of the endothelial markers (CD31, CD34, and factor VIII). The diagnosis is usually difficult and late because the patient remains asymptomatic till the onset of massive intra-abdominal bleeding. Early diagnosis and surgical management is the only potentially long –term therapeutic option. The current and accepted therapy is splenectomy. Herein, we report a case of primary splenic angiosarcoma that presented with abdominal pain, along with a review of the current literature