The effects of copper- and levonorgestrel-intrauterine devices on cervical cytology

Objective: To investigate whether there is any change in cervical cytology before and after Copper- and Levonorgestrel-Intrauterine device (IUD) insertion. Material and Methods: Pap smear results before and after Copper- and Levonorgestrel-IUD were evaluated retrospectively. All of the study specimens consisted of conventional Pap smear samples. Results: Among the women included in the study, 52 of them were inserted copper- and 24 levonorgestrel-IUD. All women had normal cytological examination results prior to IUD. There were no cases of atypia or cancer in the two groups after IUD. Non-specific inflammatory changes in 20 women (38.5%) and ASC-US in 6 women (11.5%) were found in the copper-IUD group, whereas 10 (41.7%) and 3 (12.5%) women were present in the levonorgestrel -UD group, respectively. There was no statistically significant difference between the two groups in terms of Pap smear results after IUD insertion. Conclusion: Copper- and levonorgestrel-IUD do not cause neoplasia. But they may lead to similar inflammatory changes on endometrial and cervical cells