Splenic Hamartoma: Case Report

Splenic hamartoma (Splenoma) is a rare benign malformation of the spleen characterized by the abnormal placement of normal spleen elements.It is usually asymptomatic and incidentally detected in splenectomies and autopsy.Rarely, it can cause symptoms such as thrombocytopenia, splenomegaly and anemia.A 48-year-old patient referred to the hospital with abdominal pain.Abdominal MR revealed a mass in the spleen. The patient underwent splenectomy.Hematoxylin-eosin staining revealed a lesion that was well separated from normal spleen tissue but did not have a clear capsule structure.This lesion was red pulp and no white pulp elements were seen.In the lesion, a small number of lymphocytes and hemosiderin-loaded macrophages, histiocytes, numerous vascular structures with endothelial cells, bleeding sites were observed.Immunohistochemical stainings made; extensive staining with CD34, CD31 and focal staining with CD8 was observed in vascular structures.CD3, CD20 (lymphoid cells), CD68 (histiocytes) were positive and PanCK, S100, CD1a were negative.It was diagnosed as splenic hamartoma. The case is presented because splenic hamartomas are rare and should be kept in mind in differential diagnosis