Co-existence of Primary Localized Cutaneous Amyloidosis and Diffuse Systemic Sclerosis: Case Report

Co-existence of primary localized cutaneous amyloidosis and diffuse systemic sclerosis is very rare. In a 61-year-old woman who was diagnosed as primary localized cutaneous amyloidosis with biopsy 15 years ago, additional diagnosis of diffuse systemic sclerosis was made based upon skin, locomotor system and capilloroscopy findings and autoantibody (anti- Scl70) positivity. These two autoimmune diseases, which have different aetiopathogenesis as well as diverse clinical and genetic characteristics, are rarely seen together