Risperidone Therapy in a Dog with Dissociative Syndrome

Recently describeddissociative syndrome is a progressive behavioral disorder with poor prognosis and almost 28% of animals do not seem to respond to the treatment. In the absence or lack of proper treatment, dissociation worsens and leads to severe cachexia. 4 years old Cocker spaniel-terrier mix male dog referred with complaints including receptivity loss to the environment, inattentiveness, dumb-looking periods, activity avoidance, withdrawal, and snapping the air as fly chasing without a reason. After elimination of somatic reasons, dissociative syndrome was diagnosed based on the history and behavioral examination. 0.5 ml Risperdal oral solution 1g/1m2, 100 ml (Eczac？ba？？) was used sid based on 1 mg/m2dose for 11 kg dog (0.49 m2). Before and 1 month after therapy, serum serotonin and because of reported prolactin elevation, prolactin levels were measured. Before and after therapy, there was not a beyond reference value serotonin (370.5-441.9 ng/ml) and prolactin (1.8-2.1 ng/ml) difference. Significant clinical improvement, interactive and relatively increased receptivity and contact, not completely lost, but faded and decreased hallucitative symptoms were observed