The Relationship between Red Cell Distribution Width and Ankle-Brachial Pressure Index of the Coronary Artery Lesion Severity in Patients with Stable Angina Pectoris

Objective: Ankle-brachial pressure index (ABI) is a noninvasive and inexpensive method used to identify peripheral arterial disease (PAD) in the elderly population. As a marker of PAD, ABI is widely used to predict coronary artery disease (CAD). Red cell distribution width (RDW) is a measure of the variability in the size of erythrocytes in circulation. Increases in RDW are associated with both stable and unstable CAD. In this study, we aimed to investigate whether RDW and ABI markers could provide predictive information on coronary lesion complexity using SYNTAX score (SS) in patients with stable angina pectoris (SAP). Materials and Methods: One hundred SAP patients were included in the study. Patients were divided into 40 patients with normal coronary arteries and 69 patients with CAD. Subsequently, the CAD patient group was examined by separating two subgroups (SS 1-22 (n=32) and SS >22 (n=37)) according to the SS that rated CAD severity as angiography. p <0.05 was considered significant. Results: Multivariate regression analysis showed that RDW and ABI were independently predictors of CAD (OR: 6,209, p=0.001 and OR: -2,342, p<0.001, respectively). However, the same analysis showed that ABI was better than RDW in predicting the severity of CAD (OR: 1,568, p=0,215 and OR: -1,540, p<0.001). Conclusions: In the presence of CAD has been shown that RDW increases significantly and ABI decreases significantly. It has also been found that RDW and ABI are useful variables for predicting the presence of CAD. ABI is a strong predictor of the severity of CAD than RDW