The Fatal TRALI During the Plasmapheresis A Fatal TRALI

Transfusion related acute lung injury (TRALI) is characterized by acute hypoxemia and non-cardiac edema which occurs during the transfusion or within the first 6 hours. Hypoxia, dyspnea, cyanosis, fever and tachycardia are caused by non-cardiac pulmonary edema. Transfusion-related deaths are the most common cause after hemolysis It is known that TRALI is mostly seen with plasma and platelet replacements. The risk of development of TRALI rises with the increasing number of transfusions. The use of blood and blood components for plasmapheresis and similar processes alongside the routine indications has become increasingly widespread. Therefore clinicians are more likely to meet the complications related with transfusion. In this study, we purposed to present an acute lung injury case caused by fresh frozen plasma during plasmapheresis in the context of the literature