Assessment of Acute Toxicity of Some Pharmaceuticals Effects in Aquatic Environment by Toxicity Test Methods

Purpose of this study, determination of toxicity effects of synthetic drug solutions (Flurbiprofen, Naproksen and Propranolol) by using toxicity test methods. In this study, Lepidium sativum and Daphnia magna toxicity tests were used as a method to determine potential harms to be caused to microbial ecology in receiver environment by synthetic pharmaceutical solutions were preparing certain concentrations as working samples. When Lepidium sativum and Daphnia magna toxicity tests results were evaluated, different sensitivities were determined for pharmaceutical wastewater samples of different properties. When Lepidium sativum and Daphnia magna toxicity test results were compared, Daphnia magna toxicity test method result was the most sensitive values. Daphnia magna toxicity test method results were compared in terms of times for 24 hours and 48 hours. It was observed that toxic values of pharmaceuticals were increased at 48 hours when compared to the values read at 24 hours. Flurbiprofen showed more toxic than other ingredients (Naproxen and Propranolol) both Lepidium sativum and Daphnia magna. In this study, for plants and aquatic life toxicity of some pharmaceuticals were determined and were compared in terms of sensitivity by using different toxicity test methods. So these studies, in terms of feasibility toxicity test methods are very important on pharmaceutical wastewaters. Also, looking from the viewpoint of next studies of toxicity will be lightning