Adora Risk Identification of Tricyclic Antidepresant

Objective:Tricyclic antidepressant (TCA) poisonings can cause serious clinical outcome. The Antidepressant OverdoseRisk Assessment (ADORA) criteria are used in the assessment of patients with TCA poisoning. However, the data about the benefits of these criteria in the clinical practice are insufficient to validate the ADORA criteria. The aim of this study was to determine the relationship of ADORA criteria with clinical outcome. Materials and Methods:A total of 133 patients who admitted only with TCA poisoning at a university hospital emergency department. The patients were divided into high risk and low risk groups according to ADORA criteria. Results: The mean age was 25 (range 18-55) years. Patients commonly used amitryptiline as TCA agent. Most common symptoms were dry skin, emesis and mydriasis. According to risk classification; 59.4% of the patients were in high risk group. The most common sight finding was the right axis deviation and the AVR was the R> S finding. According to ADORA's opinion, 79 patients (n = 59.4%) were high-risk carriers. The patients were discharged without any complications. As the number of ADORA positive risk scores increased, the length of hospitalization, QTc height and seizure frequency increased. Conclusion: TheADORA criteria is useful in assessment and clinical follow-up of TCA poisoning