Malignant Melanoma Metastasizing to the Stomach

Introduction: Malignant melanoma (MM) can metastasise to nearly all organs of the human body. Involvement of stomach is very rare. Case report: 52-year-old female patient applied to our hospital with abdominal pain and fatigue. Endoscopy revealed polypoid lesion in stomach. Histopathologically, there were atypical cells in lamina propria and brown pigment in some cells. These cells were positive with Melan-A and HMB-45 and negative with Cytokeratin 7 and Cytokeratin 20, immunohistochemically. This case was reported as “consistent with MM”. We have reached to former pathology report of the enucleation operation, with diagnosis of “MM with epithelioid features”. Tumor was localised in the right bulbus oculi with pathological stage pT1a. Systemic scan also revealed metastatic masses in liver. Conclusion: MM can simulate many other lesions clinically, endoscopically and histopatholgically and must be keeped in mind all the time, especially in cases with unknown primary. The patients should be screened for the primary tumor