Evaluation of Olfactor Bulbus Volume and Olfactor Sulcus Depth MRG in Idiopathic Parkinson Disease

Objective: The aim of this study was to investigate the olfactory bulb (OB) volumes and olfactory sulcus (OS) depth in patients with the idiopathic Parkinson disease (IPD). Material and Method: This study was designed as a case-control and retrospective study. Magnetic resonance imaging (MRI) examinations were performed witha 1.5 tesla MRI machine (Philips MRI Systems, Achieva Release 3.2 Level 2013-10-21, Philips Medical) with a standard head coil. Fat suppressed T2W coronal images were used for measuring OB volumes and OS depths. The data of the IPD patients were compared to the healthy controls. Results: The study comprised 39 IPD patients with the mean age of 69.07±10.48 years and 40 healthy controls with the mean age of 69.57±10.12 years. Right (30.12±6.49 vs. 39.13±6.55) and left (32.57±8.08 vs. 38.17±4.96) OB volumes and right (6.91±0.9 vs. 7.39±0.65) and left (6.82±0.7 vs. 7.38±0.58) OS depths were significantly lower in the IPD group than in the control group. Conclusion: Decreased OB volumes and OS depths have been shown in patients with IPD whereby this situation is important for the management of treatment and quality of health in these patients