THE EFFECT OF PREMATURE RETINOPATHY TREATMENT MODALITIES ON REFRACTIVE ERRORS

OBJECTIVE: To investigate the effect of treatment options on refraction in children who are treated with different treatment modalities for retinopathy of prematurity (ROP).MATERIAL AND METHODS: The study included 238 eyes of 119 patients almost 1 year old who were followed up at between April 2016 and April 2017. The patients were divided into 4 groups: Group 1 n = 153 (64.2%) without retinopathy or without treatment, Group 2 n = 36 (15.1% ) intravitreal bevacizumab (IVB), Group 3 n = 13 (5.4%) laser treatment and Group 4 n = 36 (15.1%) laser + IVB treatments. The spherical and spherical equivalan(SE) values were compared in Groups. All measurements were taken under cycloplegic conditions and with Retinomax 3 autorefractometer. Correlation with miyopia, gestational age, weight were also analysed.RESULTS: 119 cases with the mean gestational age 30.1 ± 2.8(23-36)week, the mean gestational weight 1395 ± 487(520-3000) gram, the mean incubation time 45.7 ± 31(0- 175) days were compared with treatment modalities. In group; myopia level were 0.019±0.2, 0.083±0.3, 0.76±1.64, 2.25±3.8 respectively. Hiperopia level were 2.46±1.59, 2.4±1.78, 1.41±1,39, 1.65±1,83 respectively. SE were 2.4±4.5, 1.75±1.76, -1.5±5 respectively. When we compered the laser shots and ≥ 1D myopia, it was foud 140±364-1176 ± 856 shots. It was also found that as the number of spots increased myopia frequency increased. CONCLUSIONS: Although laser treatment provide regression in advanced ROP, It may cause myopic progression. However, these babies were born very early and exposure to the physical environment rather than the maternal environment. It’s also affects myopic progression